Increased ... Increased brain connectivity between the SMN and left insula (A), DMN and right middle frontal gyrus (B) and DAN and bilateral medial prefrontal.

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Presentation transcript:

Increased ... Increased brain connectivity between the SMN and left insula (A), DMN and right middle frontal gyrus (B) and DAN and bilateral medial prefrontal cortex (C) is associated with current levels of fatigue in patients with RA. Scatter plots show positive correlations for interindividual differences in brain connectivity (Fisher-transformed r-values; x-axis) and the current fatigue ratings (y-axis). All brain illustrations are presented at P = 0.005 false discovery rate threshold. SMN: sensorimotor; DAN: dorsal attention network. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.comThis article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Rheumatology (Oxford), kez132, https://doi.org/10.1093/rheumatology/kez132 The content of this slide may be subject to copyright: please see the slide notes for details.

Fig. 2 The association between DAN-bilateral prefrontal hyperconnectivity and current fatigue ratings was reproduced ... The significant session 2 cluster (blue) is superimposed on the significant session 1 cluster (orange). Scatter plots show positive correlations for interindividual differences in brain connectivity (Fisher-transformed r-values; x-axis) and current fatigue ratings (y-axis). All brain illustrations are presented at P = 0.005 false discovery rate threshold. DAN: dorsal attention network. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.comThis article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Rheumatology (Oxford), kez132, https://doi.org/10.1093/rheumatology/kez132 The content of this slide may be subject to copyright: please see the slide notes for details.

Scatter ... Scatter plots show positive correlations for inter-individual differences in grey matter volumes (raw volumes; x-axis) and 1-week average fatigue (y-axis), corrected for total intracranial volume, age and sex. The right (R) but not left (L) putamen grey matter volumes were statistically significant. All brain illustrations are presented at P = 0.005 false discovery rate threshold. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.comThis article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Rheumatology (Oxford), kez132, https://doi.org/10.1093/rheumatology/kez132 The content of this slide may be subject to copyright: please see the slide notes for details.