Local Tumor Staging of Breast Cancer: Digital Mammography versus Digital Mammography Plus Tomosynthesis Sensitivity was higher for combined digital mammography.

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Local Tumor Staging of Breast Cancer: Digital Mammography versus Digital Mammography Plus Tomosynthesis Sensitivity was higher for combined digital mammography (DM) and digital breast tomosynthesis (DBT) (i.e., DM plus DBT) than for DM alone in the diagnosis of multicentric (51% vs 37%, P = .002) and additional ipsilateral (52% vs 44%, P = .007) lesions. The diagnostic performance of DM plus DBT was greater than that of DM alone in the assessment of bilateral breast cancer (area under the receiver operating characteristic curve [AUC], 0.74 vs 0.67; P = .02). The diagnostic performance of DBT plus DM was greater than that of DM alone only in women with nondense breasts; AUC was 0.74 versus 0.70 (P = .04) for ipsilateral lesions and 0.76 versus 0.68 (P = .02) for contralateral lesions. (a, b) Craniocaudal DM and (c, d) DBT images in a 73-year-old shows architectural distortion (arrow) in the right upper outer quadrant corresponding to the known invasive lobular cancer. DBT reveals an additional contralateral lesion in the lower outer quadrant (large arrows). Fontaine M et al. Published Online: April 9, 2019 https://doi.org/10.1148/radiol.2019182457