Volumetric Analysis of Tidemark and Vessel Perforations through Calcified Cartilage from Micro-computed Tomography: Associations with Osteoarthritis Stage

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Presentation transcript:

Volumetric Analysis of Tidemark and Vessel Perforations through Calcified Cartilage from Micro-computed Tomography: Associations with Osteoarthritis Stage S. Kauppinen, S.S. Karhula, J. Thevenot, T. Ylitalo, L. Rieppo, I. Kestilä, I. Hadjab, M.A. Finnilä, E. Quenneville, M. Garon, H.K. Gahunia, K.P. Pritzker, M. Buschmann, H.J. Nieminen, S. Saarakkala Osteoarthritis and Cartilage Volume 25, Pages S304-S305 (April 2017) DOI: 10.1016/j.joca.2017.02.512 Copyright © 2017 Terms and Conditions

Figure 1: Flow chart of μCT data analysis. Osteoarthritis and Cartilage 2017 25, S304-S305DOI: (10.1016/j.joca.2017.02.512) Copyright © 2017 Terms and Conditions

Figure 2: 3D visualization of the 600×400×Z VOIs used in the analyzes Figure 2: 3D visualization of the 600×400×Z VOIs used in the analyzes. Vessels that perforate to the tidemark surface are shown in red and the calcified tissue is shown in cyan. Osteoarthritis and Cartilage 2017 25, S304-S305DOI: (10.1016/j.joca.2017.02.512) Copyright © 2017 Terms and Conditions

Figure 3: Scatter plots of Vessel Area Fraction (VAF) and Number of vessels per mm2 (NV/A) against Tidemark roughness (TMR), Entropy of patterns (EP) and Amount of different patterns (ADP). Colors indicate different OARSI grade groups. Positive trend is observed between vessel perforation and parameters that define roughness (TMR) and local orientation variances (ADP, EP) of the tidemark. ADP is the amount of different patterns per average surface area evaluated. Osteoarthritis and Cartilage 2017 25, S304-S305DOI: (10.1016/j.joca.2017.02.512) Copyright © 2017 Terms and Conditions