Peter Kuckenberg, Caroline Kubaczka, Hubert Schorle 

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Presentation transcript:

The role of transcription factor Tcfap2c/TFAP2C in trophectoderm development  Peter Kuckenberg, Caroline Kubaczka, Hubert Schorle  Reproductive BioMedicine Online  Volume 25, Issue 1, Pages 12-20 (July 2012) DOI: 10.1016/j.rbmo.2012.02.015 Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Schematic of gene network orchestrating trophoblast development. Blue=genes implicated in specification of trophoblast fate; light blue=genes required for trophoblast maintenance; red=genes required for inner cell mass maintenance; grey=genes responsible for trophectoderm differentiation. (For interpretation of the references to colours in this figure legend, the reader is referred to the web version at this paper.) Reproductive BioMedicine Online 2012 25, 12-20DOI: (10.1016/j.rbmo.2012.02.015) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Expression of TFAP2 proteins in human placenta. Serial sections of a human placenta at 8 weeks of gestation processed with antibodies to detect TFAP2A (A) and TFAP2C (B). Red arrows=syncytiotrophoblast layer; green arrows=cytotrophoblast cells. EVT=extravillous trophoblast cells invading the decidua. Bars=100μm. (For interpretation of the references to colours in this figure legend, the reader is referred to the web version of this paper.) Reproductive BioMedicine Online 2012 25, 12-20DOI: (10.1016/j.rbmo.2012.02.015) Copyright © 2012 Reproductive Healthcare Ltd. Terms and Conditions