Case 3.

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Presentation transcript:

Case 3

Basic clinical data 51-year-old Caucassian male Tumor of the kidney 17 x 16 x 12 cm Widely necrotic (80% of tumorous mass) Vital part was grey with hemorrhagias on cut section

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Locust vs. Trixalis or Acrida

Immunohistochemistry Positive reactions AE1-AE3 EMA Vimentin Negative reactions HMB45 S-100 CAM 5.2 Actin S

Mucinous tubular and spindle cell carcinoma

Synonyms Loopoma RCC with lower-nephron differentiation Low grade collecting duct RCC Spindle and cuboidal RCC Low grade spindle cell RCC

Mucinous tubular and spindle cell carcinoma Age range 17-82 years Females are affected more frequently Usually disclosed by ultrasonographic examination for different reasons Favourable prognosis- low-grade tumors Only 2 metastatic cases in the world literature

Mucinous tubular and spindle cell carcinoma Differential diagnostics: Papillary RCC Sarcomatoid RCC Angiomyolipoma Metastasis of adenocarcinoma