The utility of automated volumetric growth analysis in a dedicated pulmonary nodule clinic  Robert J. Korst, MD, Benjamin E. Lee, MD, Glenn A. Krinsky, MD, John R. Rutledge, MAS  The Journal of Thoracic and Cardiovascular Surgery  Volume 142, Issue 2, Pages 372-377 (August 2011) DOI: 10.1016/j.jtcvs.2011.04.015 Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Correlation between nodule growth rates determined using automated volumetric software and conventional, 2-dimensional measurements as described in “Methods.” Each data point represents a comparison between 2 consecutive scans (n = 129; r = 0.69; 95% CI: 0.59-0.77; P < .00001). The Journal of Thoracic and Cardiovascular Surgery 2011 142, 372-377DOI: (10.1016/j.jtcvs.2011.04.015) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Growth rates over time for 20 biopsy-proven lung cancers. A growth index was calculated for each scan comparison as described in “Methods,” which accounts for the time interval between scans. A doubling of the growth index corresponds to a doubling of the growth rate. Each data point represents a comparison between 2 consecutive scans. Data points below the dotted line imply tumor shrinkage. The Journal of Thoracic and Cardiovascular Surgery 2011 142, 372-377DOI: (10.1016/j.jtcvs.2011.04.015) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions