M. Licker, A. Spiliopoulos, J.M. Tschopp

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Presentation transcript:

Influence of thoracic epidural analgesia on cardiovascular autonomic control after thoracic surgery M. Licker, A. Spiliopoulos, J.M. Tschopp British Journal of Anaesthesia Volume 91, Issue 4, Pages 525-531 (October 2003) DOI: 10.1093/bja/aeg212 Copyright © 2003 British Journal of Anaesthesia Terms and Conditions

Fig 1 Limits of sensory blockade achieved during continuous infusion of bupivacaine 0.125% at POD 0, POD 1 and POD 2. P<0.05 compared with POD 0. British Journal of Anaesthesia 2003 91, 525-531DOI: (10.1093/bja/aeg212) Copyright © 2003 British Journal of Anaesthesia Terms and Conditions

Fig 2 Perioperative time course of heart rate (a) and mean arterial pressure (b) in patients receiving patient-controlled analgesia (PCA) or thoracic epidural analgesia (TEA) before surgery (preop), 4 h after extubation (POD 0) and on the first and second days after surgery (POD 1 and POD 2 respectively). *P<0.05 between the two groups; †P<0.05 within a group. British Journal of Anaesthesia 2003 91, 525-531DOI: (10.1093/bja/aeg212) Copyright © 2003 British Journal of Anaesthesia Terms and Conditions

Fig 3 Perioperative time course of heart-rate variability (HRV) variables in the PCA group and TEA group. (a) Total HRV. (b) High-frequency component. (c) Low-frequency component. (d) low-frequency/high-frequency ratio (LF/HF). *P<0.05 between the two groups; **P<0.05 compared with preoperative value. British Journal of Anaesthesia 2003 91, 525-531DOI: (10.1093/bja/aeg212) Copyright © 2003 British Journal of Anaesthesia Terms and Conditions

Fig 4 Perioperative change in vascular pressure response and baroreflex sensitivity after i.v. administration of phenylephrine (PHE) and nitroglycerine (NTG) in the PCA group and TEA group. (a) Change in mean arterial pressure (MAP). (b) Baroreflex sensitivity calculated during the depressor test (NTG). (c) Baroreflex sensitivity calculated during the pressor test (PHE). *P<0.05 between the two groups; **P<0.05 compared with preoperative (preop) value. POD 0, 4 h after extubation; POD 1, first day after surgery; POD 2, second day after surgery. British Journal of Anaesthesia 2003 91, 525-531DOI: (10.1093/bja/aeg212) Copyright © 2003 British Journal of Anaesthesia Terms and Conditions