Incidence of Staphylococcus aureus with reduced susceptibility to glycopeptides in two French hospitals  M.E. Reverdy, S. Jarraud, S. Bohin-Duhreux, E.

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Incidence of Staphylococcus aureus with reduced susceptibility to glycopeptides in two French hospitals  M.E. Reverdy, S. Jarraud, S. Bohin-Duhreux, E. Buret, P. Girardo, G. Lina, F. Vandenesch, J. Etienne  Clinical Microbiology and Infection  Volume 7, Issue 5, Pages 267-272 (May 2001) DOI: 10.1046/j.1198-743x.2001.00256.x Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 1 Vancomycin and teicoplanin MICs for 81 S. aureus isolates, determined by the agar dilution (▪) or E test method (□). Clinical Microbiology and Infection 2001 7, 267-272DOI: (10.1046/j.1198-743x.2001.00256.x) Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 2 Population analysis of S. aureus strains PAD, GUE and MER and of control strain ATCC 29213. Bacteria grown overnight were serially diluted and plated on various concentrations of vancomycin-containing agar medium. Clinical Microbiology and Infection 2001 7, 267-272DOI: (10.1046/j.1198-743x.2001.00256.x) Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 3 Schematic representation of the pulsotypes of methicillin-resistant GISA or hGISA isolates (PAD245, PAD346, PAD438, GUE, LIM-2, and Mu50) with their respective origin from France or Japan, methicillin-resistant hGISA isolate (Mu3), methicillin-susceptible hGISA isolate (MER) and control isolates (ATCC 25923 and ATCC 29213). S. aureus NCTC 8325 was used as a size marker. Fragment sizes in the upper margin are in kb. Clinical Microbiology and Infection 2001 7, 267-272DOI: (10.1046/j.1198-743x.2001.00256.x) Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions

Figure 4 Composite picture showing the morphology of vancomycin-susceptible S. aureus strain ATCC 29213 (A), and morphologic abnormalities of GISA strain PAD (B) and hGISA strains GUE (C) and MER (D). Magnification × 40 000. Clinical Microbiology and Infection 2001 7, 267-272DOI: (10.1046/j.1198-743x.2001.00256.x) Copyright © 2001 European Society of Clinical Infectious Diseases Terms and Conditions