Volume 114, Issue 5, Pages (May 1998)

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Volume 114, Issue 5, Pages 1009-1015 (May 1998) Circulating xanthine oxidase and neutrophil activation during human liver transplantation Eero J. Pesonen*, Nina Linder*, Kari O. Raivio*, Annikki Sarnesto*, Risto Lapatto*, Krister Höckerstedt‡, Heikki Mäkisalo‡, Sture Andersson*,§,∥ Gastroenterology Volume 114, Issue 5, Pages 1009-1015 (May 1998) DOI: 10.1016/S0016-5085(98)70321-X Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 1 The sampling protocol. 0a, after induction of anesthesia; 0b, immediately before the anhepatic period; PV, 5 minutes after portal vein declamping; IVC, 5 minutes after inferior vena cava declamping; and HA, 3 minutes after hepatic artery declamping. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 2 Plasma concentrations of xanthine oxidase in the pulmonary artery. *P < 0.05, **P < 0.01 vs. 0a. See Figure 1 for abbreviations. Note logarithmic scale. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 3 Plasma concentration differences of xanthine oxidase between the hepatic vein (HV) and the portal vein (PV). IVC, inferior vena cava; HA, hepatic artery. *P < 0.05, **P < 0.01 HV vs. PV. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 4 Radial arterial xanthine oxidase protein concentration (○) and activity (●) of 4 patients after induction of anesthesia (0a), immediately before the anhepatic period (0b), and after hepatic artery declamping (HA). Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 5 Plasma concentrations of hypoxanthine in the pulmonary artery. See Figure 1 for abbreviations. *P < 0.05, **P < 0.01 vs. 0a. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 6 Plasma concentration differences of hypoxanthine between the hepatic vein (HV) and the portal vein (PV). IVC, inferior vena cava; HA, hepatic artery. *P < 0.05 HV vs. PV. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 7 Plasma concentrations of xanthine in the pulmonary artery. See Figure 1 for abbreviations. *P < 0.05, **P < 0.01 vs. 0a. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 8 Plasma concentration differences of xanthine between the hepatic vein (HV) and the portal vein (PV). IVC, inferior vena cava; HA, hepatic artery. *P < 0.05 HV vs. PV. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 9 Plasma concentrations of lactoferrin in the pulmonary artery. See Figure 1 for abbreviations. *P < 0.05, **P < 0.01 vs. 0a. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 10 Plasma concentration differences of lactoferrin between the hepatic vein (HV) and the portal vein (PV). IVC, inferior vena cava; HA, hepatic artery. **P < 0.01 HV vs. PV. Gastroenterology 1998 114, 1009-1015DOI: (10.1016/S0016-5085(98)70321-X) Copyright © 1998 American Gastroenterological Association Terms and Conditions