Point-of-Care vs Laboratory INR Testing to Optimize Anticoagulation Management.

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Presentation transcript:

Point-of-Care vs Laboratory INR Testing to Optimize Anticoagulation Management

Warfarin Use and Prothrombin Time Testing

PT Testing

PT Standardization

Differences Between POCT and Laboratory INR Testing

Potential Sources of Error for Any Lab Test

Interference Limitations With INR

Variability of Lab INR

Advantages of POCT

In Support of PST

INR Measurements With POC Device Demonstrate Accuracy in Clinic Study

POCT and Lab Results Are NOT an "Apples to Apples" Comparison

Who Is Correct?

Manufacturer Regulation

Scenario Patient Blood Sent to 5 Laboratories

Local Example of INR Performance PST vs Laboratory

How to Compare INR Results?

Everyone Has an Equal Role

MGH Standardized Patient Assessment for INRs ≥ 5

How to Address Variability Between POC and Lab INRs

Calibration Standardization Requirements

Managing Anticoagulation Needs Based on POC INR Test Values

POC INR Testing

Precision vs Accuracy

Thrombotic and Hemorrhagic Reserve for a Patient With a Target INR of 3.0

Conclusion

Abbreviations

Abbreviations (cont)