The Pathogenesis of Alopecia Areata in Rodent Models Kevin J. McElwee, Pia Freyschmidt-Paul, John P. Sundberg, Rolf Hoffmann  Journal of Investigative Dermatology Symposium Proceedings  Volume 8, Issue 1, Pages 6-11 (June 2003) DOI: 10.1046/j.1523-1747.2003.12164.x Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Relevance of rodent models to human alopecia areata. Human alopecia areata involves considerable variation in phenotype and probably also involves genotype heterogeneity within a restricted range. An inbred rodent model may not represent all human phenotype or genotype presentations, but will be relevant to a subset of alopecia areata-affected individuals. Where a rodent model and human phenotype and genotype coincides, each rodent model represents a subset of the human population. Each rodent model may represent unique or overlappingsubsets. Journal of Investigative Dermatology Symposium Proceedings 2003 8, 6-11DOI: (10.1046/j.1523-1747.2003.12164.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Alopecia areata pathogenesis and perpetuation. Journal of Investigative Dermatology Symposium Proceedings 2003 8, 6-11DOI: (10.1046/j.1523-1747.2003.12164.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 3 Practical and theoretical therapeutic interventions in alopecia areata pathogenesis. Journal of Investigative Dermatology Symposium Proceedings 2003 8, 6-11DOI: (10.1046/j.1523-1747.2003.12164.x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions