Imbalance in the peritoneal levels of interleukin 1 and its decoy inhibitory receptor type II in endometriosis women with infertility and pelvic pain

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Imbalance in the peritoneal levels of interleukin 1 and its decoy inhibitory receptor type II in endometriosis women with infertility and pelvic pain Ali Akoum, Ph.D., Mahéra Al-Akoum, M.D., André Lemay, M.D., Ph.D., Rodolphe Maheux, M.D., Mathieu Leboeuf, M.D. Fertility and Sterility Volume 89, Issue 6, Pages 1618-1624 (June 2008) DOI: 10.1016/j.fertnstert.2007.06.019 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Distribution of interleukin-1 receptor type II (IL1R2) (A) and interleukin-1β (IL1β) (B) concentrations in the peritoneal fluid of normal controls (NC) and patients with endometriosis (E) according to the stage of the disease. The horizontal lines represent the mean for each set of data. ∗P<.05, ∗∗P<.01, ∗∗∗P<.001, compared to NC. Fertility and Sterility 2008 89, 1618-1624DOI: (10.1016/j.fertnstert.2007.06.019) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Distribution of interleukin-1 receptor type II (IL1R2) (A) and interleukin-1β (IL1β) (B) concentrations in the peritoneal fluid of normal controls (NC), normal infertile women without endometriosis (NI), and women with endometriosis who are fertile (EF) or infertile (EI). The horizontal lines represent the mean for each set of data. ∗P<.05, ∗∗P<.01 compared to NC; ††P<.01 compared to NI. Fertility and Sterility 2008 89, 1618-1624DOI: (10.1016/j.fertnstert.2007.06.019) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Distribution of interleukin-1 receptor type II (IL1R2) (A) and interleukin-1β (IL1β) (B) concentrations in the peritoneal fluid of normal controls (NC), normal women reporting pelvic pain without evidence of endometriosis (NWP), and women with endometriosis without (EWOP) or with (EWP) pelvic pain. The horizontal lines represent the mean for each set of data. ∗P<.05, ∗∗∗P<.001 compared to NC. Fertility and Sterility 2008 89, 1618-1624DOI: (10.1016/j.fertnstert.2007.06.019) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions