Impact of Diabetes Mellitus on the Association of Vascular Disease Before Transplantation With Long-term Transplant and Patient Outcomes After Kidney.

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Impact of Diabetes Mellitus on the Association of Vascular Disease Before Transplantation With Long-term Transplant and Patient Outcomes After Kidney Transplantation: A Population Cohort Study Wai H. Lim, David W. Johnson, Carmel M. Hawley, Elaine Pascoe, Germaine Wong American Journal of Kidney Diseases Volume 71, Issue 1, Pages 102-111 (January 2018) DOI: 10.1053/j.ajkd.2017.08.018 Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Cumulative incidence function curves of (A) death-censored graft loss (DCGL) and (B) death with a functioning graft (DWFG) after kidney transplantation stratified by cumulative vascular disease burden, adjusted for the competing risk for DWFG and DCGL, respectively. American Journal of Kidney Diseases 2018 71, 102-111DOI: (10.1053/j.ajkd.2017.08.018) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Forest plots show the adjusted subdistribution hazard ratio (HR) with 95% confidence interval (95% CI) of the associations between cumulative vascular disease burden, cardiovascular disease (CVD) mortality, infection-related mortality, cancer-related mortality, and other vascular disease–related mortality. Models adjusted for donor and recipient age, waiting time, body mass index, sex, transplantation era, and race. Estimates of subdistribution HRs were derived from the competing-risk models using the Fine and Gray method. American Journal of Kidney Diseases 2018 71, 102-111DOI: (10.1053/j.ajkd.2017.08.018) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Cumulative incidence function curves of cardiovascular disease (CVD) mortality stratified by cumulative vascular disease burden, adjusted for the competing risk for non–CVD-related mortality. American Journal of Kidney Diseases 2018 71, 102-111DOI: (10.1053/j.ajkd.2017.08.018) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

Figure 4 Forest plots show adjusted hazard ratios (HRs) or adjusted subdistribution HRs with 95% confidence intervals (CIs) of the associations between cumulative vascular disease burden, all-cause mortality, overall transplant loss, death with functioning transplant, and cardiovascular disease (CVD) mortality according to pretransplantation diabetes status. Models adjusted for donor and recipient age, waiting time, body mass index, sex, transplantation era, and race. #Estimates of subdistribution HRs were derived from competing-risk models using the Fine and Gray method. American Journal of Kidney Diseases 2018 71, 102-111DOI: (10.1053/j.ajkd.2017.08.018) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions