Templates of the cartilage layers of the patellofemoral joint and their use in the assessment of osteoarthritic cartilage damage Z.A Cohen, Ph.D., V.C.

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Presentation transcript:

Templates of the cartilage layers of the patellofemoral joint and their use in the assessment of osteoarthritic cartilage damage Z.A Cohen, Ph.D., V.C Mow, Ph.D., J.H Henry, M.D., W.N Levine, M.D., G.A Ateshian, Ph.D. Osteoarthritis and Cartilage Volume 11, Issue 8, Pages 569-579 (August 2003) DOI: 10.1016/S1063-4584(03)00091-8

Fig. 1 Breakdown of normal and OA joints and corresponding imaging modalities. Osteoarthritis and Cartilage 2003 11, 569-579DOI: (10.1016/S1063-4584(03)00091-8)

Fig. 2 Magnetic resonance images (3D SPGR, 1.5T GE magnet, TR=55ms, TE=5ms, flip angle=40°) highlighting cartilage layer: (a) right knee of normal male cadaver, 55 years old at time of death and (b) left knee of 48 years old female patient. Osteoarthritis and Cartilage 2003 11, 569-579DOI: (10.1016/S1063-4584(03)00091-8)

Fig. 3 Schematic for averaging (a) femoral and (b) patellar surfaces. Osteoarthritis and Cartilage 2003 11, 569-579DOI: (10.1016/S1063-4584(03)00091-8)

Fig. 4 Average maps for the femoral and patellar surfaces of 14 non-arthritic PFJ joints: (a) mean cartilage thickness; (b) SD of cartilage thickness; (c) coefficient of variation of cartilage thickness. Osteoarthritis and Cartilage 2003 11, 569-579DOI: (10.1016/S1063-4584(03)00091-8)

Fig. 5 (a) Cartilage thickness maps for left knee of a 51-year-old female patient diagnosed with PFJ OA (tij), using the patient's articular surface topography; (b) normalized difference maps for same patient (uij), plotted on the (reflected) articular surface topography from the normal template (Fig. 4); (c) scaled difference maps for same patient (vij). Osteoarthritis and Cartilage 2003 11, 569-579DOI: (10.1016/S1063-4584(03)00091-8)

Fig. 6 Average maps for the femoral and patellar surfaces of 33 knees with PFJ OA: (a) mean cartilage thickness map, plotted on mean articular surface topography of OA joints; (b) normalized difference maps against the normal template, plotted on the articular surface topography from the normal template; (c) scaled difference maps. Osteoarthritis and Cartilage 2003 11, 569-579DOI: (10.1016/S1063-4584(03)00091-8)

Fig. 7 Comparison of area-fraction at difference SD levels for normal joints and patient joints: femurs (a) and patellae (b). Osteoarthritis and Cartilage 2003 11, 569-579DOI: (10.1016/S1063-4584(03)00091-8)