Volume 77, Issue 8, Pages (April 2010)

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Presentation transcript:

Volume 77, Issue 8, Pages 655-656 (April 2010) Journal Club Kidney International Volume 77, Issue 8, Pages 655-656 (April 2010) DOI: 10.1038/ki.2010.66 Copyright © 2010 International Society of Nephrology Terms and Conditions

PRR is required for Wnt/β-catenin signaling and antero-posterior neural patterning in Xenopus. Xenopus embryos injected with control (top) or PRR antisense morpholino oligonucleotides in the absence (middle) or presence of wild-type human PRR mRNA (bottom). Kidney International 2010 77, 655-656DOI: (10.1038/ki.2010.66) Copyright © 2010 International Society of Nephrology Terms and Conditions

Figure (a) Twenty-four-hour plasma aldosterone in wild-type (WT) and Cry-null mice. (b) Plasma renin activity in WT and Cry-null mice at CT0 and CT12. CT0 and CT12, beginning of subjective day and night, respectively. Kidney International 2010 77, 655-656DOI: (10.1038/ki.2010.66) Copyright © 2010 International Society of Nephrology Terms and Conditions

Figure Carbohydrate levels in kidney cortex and AR expression in renal tissues in experimental mice. (a) There was significant elevation of sorbitol and fructose in mice with hindlimb ischemia. Treatment with ARI significantly inhibited the change. There was no alteration in AR knockout (KO) mice after ischemia. (b) AR expression in renal cortex and medulla was comparable in experimental mice with or without hindlimb ischemia. There was no expression in AR-KO mice. AR, aldose reductase; ARI, AR inhibitor; I, ischemia; mAR, mouse AR; NS, not significant; WT, wild-type. Kidney International 2010 77, 655-656DOI: (10.1038/ki.2010.66) Copyright © 2010 International Society of Nephrology Terms and Conditions