Algorithm for the diagnosis of NAFLD and NASH in patients with prediabetes or T2DM in clinical practice. Algorithm for the diagnosis of NAFLD and NASH.

Slides:



Advertisements
Similar presentations
February 16, Gainesville, Florida
Advertisements

Pacemakers and MRI An outdated contraindication? Emily Myers Research in Allied Health East Tennessee State University.
Hepatic Steatosis Chen-Yu Wang
Role of Imaging in diagnosis A Vohrah. First time it has been run entirely by radiology Hope we don’t have too many hiccups Explain the role of imaging.
Nonalcoholic Fatty Liver Disease / Nonalcoholic Steatohepatitis 소화기내과 R3 신아리 1.
Date of download: 7/5/2016 From: Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus:
Figure 1 Proposed risk stratification for patients with NAFLD
Medical Imaging Technologies
NASH: State of the Science
Abnormal Liver Tests and Fatty Liver on Ultrasound
When Should Abdominal Magnetic Resonance Imaging Be Used?
Imaging studies. Imaging studies. Proton density fat-saturated MRI sequence demonstrates an increased signal within the semimembranosus and biceps femoris.
MRI and MRE for non-invasive quantitative assessment of hepatic steatosis and fibrosis in NAFLD and NASH: Clinical trials to clinical practice  Parambir.
Recognizing and Staging the Severity of NASH: What Tools Do We Have?
Non-alcoholic fatty liver disease and cardiovascular risk: Pathophysiological mechanisms and implications  Sven M. Francque, Denise van der Graaff, Wilhelmus.
کبد چرب. کبد چرب چاقی و ارتباط آن با کبد چرب چاقی  تجمع بافت چربی  ترشح فاکتور مانند ویسفاتین  کبد چرب * عوارض چاقی : الف - دیابت نوع  ب – فشار.
More Than Meets the Eye: Identifying Who Is at Risk for NASH
Impact of PNPLA3 variants on liver histology of 168 patients with HIV infection and chronic hepatitis C  C. Sagnelli, M. Merli, C. Uberti-Foppa, H. Hasson,
Genetics and epigenetics of NAFLD and NASH
How to Approach a Patient With Nonalcoholic Fatty Liver Disease
Modulation of the intensiveness of glucose lowering in type 2 diabetes
Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro
Non-invasive diagnosis of non-alcoholic fatty liver disease
Features, Diagnosis, and Treatment of Nonalcoholic Fatty Liver Disease
Antihyperglycemic therapy in type 2 diabetes: general recommendations
When Should Abdominal Magnetic Resonance Imaging Be Used?
The risk of DR progression as related to mean HbA1c during DCCT
Prevalence of NAFLD (panel A) and advanced fibrosis (panel B) in the general population and in patients with T2DM according to different diagnostic tools.
Allison L. Ruff, MD, Kathryn Teng, MD, Bo Hu, PhD, Michael B
Figure 3 Clinical algorithms in the management of NASH and diabetes mellitus Figure 3 | Clinical algorithms in the management of NASH and diabetes mellitus.
Abstracts from Around the World
IMAGING-BASED MODALITIES IN NAFLD
by Agata Juszczak, Rebecca Pryse, Andrew Schuman, and Katharine R Owen
Rohit Loomba, MD, MHSc  Clinical Gastroenterology and Hepatology 
Effects of free omega-3 carboxylic acids and fenofibrate on liver fat content in patients with hypertriglyceridemia and non-alcoholic fatty liver disease:
Abnormal Liver Tests and Fatty Liver on Ultrasound
Brian D. Williamson et al. JACEP 2017;3:
The genetics of alcohol dependence and alcohol-related liver disease
Gender differences in diabetes prevalence in 2009 in the general Portuguese population patients and in patients with CAP. Diabetes prevalence is higher.
Volume 150, Issue 3, Pages (March 2016)
Volume 142, Issue 4, Pages e6 (April 2012)
Selonsertib in NASH: phase 2
NGM282 in NASH: 3 mg QD (phase 2)
GS-9674 in NASH: a phase 2 study
Diagnostic Management of Suspected Acute Cyst Complication
The rates of occurrences of cardiovascular, cerebrovascular, and all events expressed in cases per 1, 000 patient-years in diabetic subgroups divided by.
Response to abnormal liver blood tests.
An algorithm depicting the basic approach to the Charcot foot
The incidence of insulin-treated type 1 diabetes in the first 35 years of life. The incidence of insulin-treated type 1 diabetes in the first 35 years.
FMD and PWV of patients with diabetes with (T2DM-SCT) or without (T2DM) SCT and of healthy individuals with (SCT) or without (CONT) SCT. FMD measured at.
Left columns: Plasma glucose and serum insulin concentrations, circulating TF-PCA, and FVIIa activity before and during 24 h of selective hyperglycemia.
Algorithm for the management of patients with prediabetes or T2DM and definite NASH. This suggested therapeutic algorithm is based on the safety and efficacy.
The underlying physiological basis of the HOMA model.
Selection of DFU patients and non-DFU controls
Idiopathic Intracranial Hypertension
Representative study BG profiles from the forearm and the fingertip of six patients with diabetes. Representative study BG profiles from the forearm and.
Forest plot and pooled estimates of the effect of NAFLD on the risk of incident diabetes in 16 eligible studies, stratified by length of follow-up (FU)
Relationship between changes in mean fat cell volume and insulin sensitivity (M values) after gastric bypass of obese women. Relationship between changes.
Several genetic, environmental, lipid partitioning, and biochemical factors, shown on the left, promote the development of subclinical inflammation and.
RBP4 and glucose metabolism.
NAFLD and NASH in Europe and Canada
A: Probability of retinopathy-free survival.
Mean HbA1c (%) and estimated marginal mean SH rate (per 100 patient-years) adjusted for sex, age-group at diagnosis, and diabetes duration, by time period,
GDF-15 levels in progressors and nonprogressors in albuminuria (case and control subjects) for patients with T2DM and nondiabetic patients with HT. A:
How to Approach a Patient With Nonalcoholic Fatty Liver Disease
Liver fat content and impairment of insulin sensitivity and β-cell function in obese children and adolescents. Liver fat content and impairment of insulin.
Introduction to Abbreviated Liver MRI Protocols
Metabolic Impact of Nonalcoholic Steatohepatitis in Obese Patients
Sensitivity and specificity of HbA1c, FPG, and 2hPG in identifying persons who developed diabetes within 10 years of screening among children and adolescents.
Insulin secretion (hyperglycemic clamp) (A), insulin sensitivity (hyperinsulinemic-euglycemic clamp) (B), and glucose disposition index (GDI) (C) in adolescents.
Presentation transcript:

Algorithm for the diagnosis of NAFLD and NASH in patients with prediabetes or T2DM in clinical practice. Algorithm for the diagnosis of NAFLD and NASH in patients with prediabetes or T2DM in clinical practice. This suggested algorithm is based on the authors’ interpretation of available evidence. MR, magnetic resonance; US, ultrasound. *Based on results from more sensitive tests such as liver 1H-MRS, MRI-proton density fat fraction, or CAP. #Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M and/or transmembrane 6 superfamily member 2 (TM6SF2) E167 K. Fernando Bril, and Kenneth Cusi Dia Care 2017;40:419-430 ©2017 by American Diabetes Association