Quantifying “normalized” regional left ventricular contractile function in ischemic coronary artery disease Matthew C. Henn, MD, Brian P. Cupps, PhD,

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Presentation transcript:

Quantifying “normalized” regional left ventricular contractile function in ischemic coronary artery disease Matthew C. Henn, MD, Brian P. Cupps, PhD, Julia Kar, PhD, Kevin Kulshrestha, Danielle Koerner, Alan C. Braverman, MD, Michael K. Pasque, MD The Journal of Thoracic and Cardiovascular Surgery Volume 150, Issue 1, Pages 240-246 (July 2015) DOI: 10.1016/j.jtcvs.2015.03.049 Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 The display of “normalized,” microregional contractile function by intuitive z-score color contour mapping (<1 SD = blue; 1-2 SDs = yellow; >2 SDs = red) over patient-specific 3D left ventricular geometry for all 60 patients with coronary artery disease. The resolution of each MRI image is 72 pixels/inch; the 3D color contour maps are 300 pixels/inch. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 240-246DOI: (10.1016/j.jtcvs.2015.03.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 The display of “normalized,” microregional contractile function by z-score color contour mapping in a healthy volunteer (left) is contrasted with that of a patient (right) with severe, regional, contractile impairment secondary to myocardial infarction (<1 SD = blue; 1-2 SDs = yellow; >2 SDs = red). The Journal of Thoracic and Cardiovascular Surgery 2015 150, 240-246DOI: (10.1016/j.jtcvs.2015.03.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Comparison of a SPECT image (top) to MRI-based, “normalized,” microregional contractile function (bottom) in the same patient with coronary artery disease. ANT, Anterior; SEPT, septal; LAT, lateral; INF, inferior. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 240-246DOI: (10.1016/j.jtcvs.2015.03.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

Magnetic resonance imaging–based, “normalized,” regional contractile function in a patient with coronary artery disease. The Journal of Thoracic and Cardiovascular Surgery 2015 150, 240-246DOI: (10.1016/j.jtcvs.2015.03.049) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions