Osmosis Posmotic = nRT/V =(n/V) * RT = i M * R’T i: van’t Hoff factor M: molarity R: J/k mol R’: L atm/K mol.

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Presentation transcript:

Osmosis Posmotic = nRT/V =(n/V) * RT = i M * R’T i: van’t Hoff factor M: molarity R: 8.3145 J/k mol R’: 0.0821 L atm/K mol

Unequal distribution Intracellualr Extracellular +: K+ > Mg + > Na + -: PO4 2- > Protein > HCO3- Extracellular +: Na + > K + > Ca 2+ -: Cl- > HCO3- > Protein

Bert Sakmann The Nobel Prize in Physiology or Medicine 1991

http://www.biochem.mpg.de/mnphys/publications/01zecfro/index.html

Ferbeyre G, Lowe SW. Nature 415, 26-27

Take home message Membrane transport Cell cycle Passive: simple diffusion / osmosis / facilitated diffusion (channel/carrier mediated) Active transport Cell cycle Interphase Prophase Metaphase Anaphase Telophase