Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis Reshef Tal,

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Presentation transcript:

Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis Reshef Tal, M.D., Ph.D., Oded Tal, Ph.D., Benjamin J. Seifer, B.S.M.E., David B. Seifer, M.D. Fertility and Sterility Volume 103, Issue 1, Pages 119-130.e3 (January 2015) DOI: 10.1016/j.fertnstert.2014.09.041 Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Flowchart of the search and selection strategy. n = number of studies; N = number of study participants. Fertility and Sterility 2015 103, 119-130.e3DOI: (10.1016/j.fertnstert.2014.09.041) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Figure 2 (A) Forest plot of diagnostic OR for AMH as a predictor of implantation. (B–D) Forest plots of diagnostic OR for AMH as a predictor of clinical pregnancy in (B) women with unspecified ovarian reserve; (C) women with DOR; and (D) women with PCOS. Fertility and Sterility 2015 103, 119-130.e3DOI: (10.1016/j.fertnstert.2014.09.041) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Figure 3 (A) Summary ROC curve of AMH in the prediction of implantation after ART. (B–D) Summary ROC curves of AMH in the prediction of clinical pregnancy after ART in (B) women with unspecified ovarian reserve; (C) women with DOR; and (D) women with PCOS. Fertility and Sterility 2015 103, 119-130.e3DOI: (10.1016/j.fertnstert.2014.09.041) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Funnel plots for assessment of publication bias. All plots are symmetrical about the average value, suggesting that smaller studies tend to report sensitivity and specificity similar to those for larger studies. Fertility and Sterility 2015 103, 119-130.e3DOI: (10.1016/j.fertnstert.2014.09.041) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 Funnel plots for assessment of publication bias. The plot visually demonstrates asymmetry, which was confirmed by the statistical test for asymmetry. Fertility and Sterility 2015 103, 119-130.e3DOI: (10.1016/j.fertnstert.2014.09.041) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions