Raheel Rizwan, MD, Farhan Zafar, MD, Roosevelt Bryant, MD, James S

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The Number of Refusals for Donor Organ Quality Does Not Impact Heart Transplant Outcomes in Children Raheel Rizwan, MD, Farhan Zafar, MD, Roosevelt Bryant, MD, James S. Tweddell, MD, Angela Lorts, MD, Clifford Chin, MD, David L. Morales, MD The Annals of Thoracic Surgery Volume 105, Issue 4, Pages 1223-1230 (April 2018) DOI: 10.1016/j.athoracsur.2017.10.006 Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Number (No.) of transplants performed utilizing donor organs with different numbers of refusals due to donor quality: (A) for total duration of study period; and (B) for old era, before 2008 (blue bars), and current era, 2008 to 2015 (orange bars). The Annals of Thoracic Surgery 2018 105, 1223-1230DOI: (10.1016/j.athoracsur.2017.10.006) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan-Meier comparison of recipients who received a donor organ with zero to three refusals due to quality (RDQ-low [blue lines]), and recipients who received a donor organ with more than three RDQ (RDQ-high [green lines]), for (A) posttransplant patient survival, and (B) freedom from retransplantation (Re-Tx). The Annals of Thoracic Surgery 2018 105, 1223-1230DOI: (10.1016/j.athoracsur.2017.10.006) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Posttransplant Kaplan-Meier survival comparison of matched cohorts (ratio 1:1) of recipients by organ refusals due to quality (RDQ) who received a donor organ with zero to three RDQ (RDQ-low [blue line]) and recipients who received a donor organ with more than three RDQ (RDQ-high [green line]). Matching variables (recorded at time of transplant): age, transplant year, transplant diagnosis, glomerular filtration rate <60 mL · min−1 · 1.73 m−2, and ventilator support. The Annals of Thoracic Surgery 2018 105, 1223-1230DOI: (10.1016/j.athoracsur.2017.10.006) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Kaplan-Meier survival curves comparing recipients who received organs with refusals due to quality (RDQ) in the RDQ-low group (RDQ-L 0 to 3 [blue line]) with the RDQ-high group (RDQ-H more than 3 [green line]), and with recipients who received donor organs with more than six RDQ (aqua line), more than nine RDQ (orange line), more than 12 RDQ (purple line), and more than 15 RDQ (red line). The Annals of Thoracic Surgery 2018 105, 1223-1230DOI: (10.1016/j.athoracsur.2017.10.006) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions

Supplemental Figure 1 The Annals of Thoracic Surgery 2018 105, 1223-1230DOI: (10.1016/j.athoracsur.2017.10.006) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions

Supplemental Figure 2 The Annals of Thoracic Surgery 2018 105, 1223-1230DOI: (10.1016/j.athoracsur.2017.10.006) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions