Effect of β-adrenergic agonists on mucociliary clearance

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Presentation transcript:

Effect of β-adrenergic agonists on mucociliary clearance William D. Bennett, PhD Journal of Allergy and Clinical Immunology Volume 110, Issue 6, Pages S291-S297 (December 2002) DOI: 10.1067/mai.2002.129704 Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 1 Percentage clearances at 1 hour for healthy subjects, patients with asthma, and patients with chronic bronchitis (CB) after acute treatment with placebo versus terbutaline (0.25 mg subcutaneously.) (Data from Camner P, Strandberg K, Philipson K. Increased mucociliary transport by adrenergic stimulation. Arch Environ Health 1976;39:79-82. Data from Mossberg B, Strandberg K, Philipson K, Camner P. Tracheobronchial clearance in bronchial asthma: response to beta-adrenoceptor stimulation. Scand J Respir Dis 1976;57:119-28.) Journal of Allergy and Clinical Immunology 2002 110, S291-S297DOI: (10.1067/mai.2002.129704) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 2 Percentage clearances at 1 hour for healthy subjects after acute treatment with low- versus high-dose nebulized albuterol (see text for dosing). Also given are the mean airway resistances before and after treatment with low versus high dose. Asterisk indicates P < .05 for comparison with control or pretreatment values. Data from Bennett WD, et al. J Aerosol Med 1993;6:53-62. Journal of Allergy and Clinical Immunology 2002 110, S291-S297DOI: (10.1067/mai.2002.129704) Copyright © 2002 Mosby, Inc. Terms and Conditions