Genetically Determined Partial Complement C4 Deficiency States Are Not Independent Risk Factors for SLE in UK and Spanish Populations  Lora Boteva, David L. Morris, Josefina Cortés-Hernández, Javier Martin, Timothy J. Vyse, Michelle M.A. Fernando  The American Journal of Human Genetics  Volume 90, Issue 3, Pages 445-456 (March 2012) DOI: 10.1016/j.ajhg.2012.01.012 Copyright © 2012 The American Society of Human Genetics Terms and Conditions

Figure 1 Total Complement C4, C4A, and C4B GCN Distributions in UK and Spanish SLE From top to bottom, the histograms demonstrate total complement C4, C4A, and C4B GCN distributions in healthy controls (blue) and SLE cases (red) from the UK and Spain. The American Journal of Human Genetics 2012 90, 445-456DOI: (10.1016/j.ajhg.2012.01.012) Copyright © 2012 The American Society of Human Genetics Terms and Conditions

Figure 2 Frequency of the Complement C4A exon 29 CT Insertion in UK and Spanish SLE Cohorts The histogram shows the frequency of the loss-of-function complement C4A exon 29 CT insertion in healthy controls (blue) and SLE cases (red) from the UK and Spain. The American Journal of Human Genetics 2012 90, 445-456DOI: (10.1016/j.ajhg.2012.01.012) Copyright © 2012 The American Society of Human Genetics Terms and Conditions