Do Cancer Cells Care If Their Host Is Hungry?

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Presentation transcript:

Do Cancer Cells Care If Their Host Is Hungry? Michael Pollak Cell Metabolism Volume 9, Issue 5, Pages 401-403 (May 2009) DOI: 10.1016/j.cmet.2009.04.006 Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 1 Cancer Endocrinology Meets Whole Organism Energy Homeostasis Recent data from the Sabatini lab add to prior evidence suggesting that dietary restriction limits growth of certain cancers through its effects on insulin and IGF-I, rather through reduced energy supply to cancer cells. This is contributes to the rationale for investigations of novel cancer therapies that target insulin and IGF-I signaling. Cell Metabolism 2009 9, 401-403DOI: (10.1016/j.cmet.2009.04.006) Copyright © 2009 Elsevier Inc. Terms and Conditions