Expression profile of long noncoding rnas in osteoarthritis patients

Slides:



Advertisements
Similar presentations
Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
Advertisements

Jiaojiao Lü, Lingyan Huang, Xie Wu, Weijie Fu, Yu Liu
Electrical stimulation for pain relief in knee osteoarthritis: systematic review and network meta-analysis  C. Zeng, H. li, T. Yang, Z.-h. Deng, Y. Yang,
M. Fu, G. Huang, Z. Zhang, J. Liu, Z. Zhang, Z. Huang, B. Yu, F. Meng 
A bioinformatic analysis of microRNAs role in osteoarthritis
Electrical stimulation for pain relief in knee osteoarthritis: systematic review and network meta-analysis  C. Zeng, H. li, T. Yang, Z.-h. Deng, Y. Yang,
D. N. Clements, B. Sc. , B. V. Sc. , S. D. Carter, Ph. D. , J. F
Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA  Y. Xu, M.J. Barter, D.C. Swan,
Mesenchymal stromal cells for cartilage repair in osteoarthritis
Z. Zhang, Y. Kang, Z. Zhang, H. Zhang, X. Duan, J. Liu, X. Li, W. Liao 
The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-α and MMP13  S.W. Jones, Ph.D., G.
Next-generation Sequencing Identifies Articular Cartilage and Subchondral Bone Mirnas after ESWT on Early Osteoarthritis Knee  C.-J. Wang, J.-H. Cheng,
P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung 
C. -H. Chou, M. T. M. Lee, I. -W. Song, L. -S. Lu, H. -C. Shen, C. -H
S. Gavard  Osteoarthritis and Cartilage 
Gene expression profiling for confirmation of effects of DNA polymeric molecules on in vitro arthritis model  H.-J. Kim, A. Baek, M. Kim, S.-R. Cho  Osteoarthritis.
Metabolomic analysis of human plasma reveals that arginine is depleted in knee osteoarthritis patients  W. Zhang, G. Sun, S. Likhodii, M. Liu, E. Aref-Eshghi,
S. Kashyap, H. Zhang, M. Sonka  Osteoarthritis and Cartilage 
The effects of dynamic viscosity on cartilage mechanics
K.D. Allen, C.J. Coffman, Y.M. Golightly, K.M. Stechuchak, F.J. Keefe 
Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives  Y. Henrotin  Osteoarthritis and Cartilage 
Pre-operative expectation predicts 12-month post-operative outcome among patients undergoing primary total hip replacement in European orthopaedic centres 
Osteoarthritis and Cartilage
Automatic cartilage segmentation and measurement for diagnosis of OA using 3D box and Gaussian filters  X. Cui, S. Li, M. Yu, H. Kim, K.-S. Kwack, B.-H.
K. Zou, M.D., G. Liu, M.D., T. Wu, M.D., L. Du, M.D. 
Changes in biochemical markers and prediction of effectiveness of intra-articular hyaluronan in patients with knee osteoarthritis  M. Hasegawa, M.D.,
Effect of mechanical stress on the hypertrophic differentiation related gene expression in cultured chondrocytes  H. Inoue, Y. Arai, R. Terauchi, S. Nakagawa,
Z. Zhang, W. Liao, Z. Zhang, X. Duan, C. Hou 
The differences on extracellular matrix among each portion of meniscus
Efficacy and safety of intraarticular hyaluronic acid in the treatment of hip osteoarthritis: a systematic review  J.C. Fernández López, M.D., Ph.D.,
Osteoarthritis pain mechanisms: basic studies in animal models
P.J. Fanning, C.M. Raskett, N.H. Farina, D.C. Ayers, J.B. Lian 
P. Yuan, X. Zhang, W. Yang, W. Kang, B. Yang, J. li, B. Chen, X. Li, B
Osteoarthritis year 2013 in review: genetics and genomics
Time to be positive about negative data?
Landscape of Long Noncoding RNAs in Psoriatic and Healthy Skin
Gene expression variation in human meniscus: molecular and clinical implications for cartilage homeostasis and early osteoarthritis development  M.F.
B. Vafaeian, S. Adeeb, M. El-Rich, J. Jaremko 
Different responses of healthy, relative healthy and OA chondrocytes with IL1β treatment under hypoxia and normoxia  X. Huang, L. Zhong, J. Post, M. Karperien 
Identification of differentially expressed genes in trabecular bone from the iliac crest of osteoarthritic patients  E. Sánchez-Sabaté, L. Alvarez, E.
M.L. Roemhildt, A.E. Gauthier  Osteoarthritis and Cartilage 
Who should have a joint replacement? A plea for more ‘phronesis’
Structural Damage of the Thumb Base in Patients With Hand Osteoarthritis, Assessment by Magnetic Resonance Imaging Compared to Standard Radiography  S.
Three dimensional distribution of hip cartilage t2 mapping assessed by radial mr imaging: comparison between healthy volunteers and patients with hip.
Emerging role of endothelin receptor type B in regulating chondrogenic and hypertrophic changes of human mesenchymal stem cells  M. Au, M. Zhu, W.-J.
Knocking out or pharmaceutical inhibition of fatty acid binding protein 4 (Fabp-4) alleviates osteoarthritis induced by a very high fat diet in mouse 
N. Khalaj, N.A. Osman, W. Wan Abas, A. Mokhtar 
Z. Huang, T. Stabler, F. Pei, V. Kraus  Osteoarthritis and Cartilage 
R.H. Brophy, B. Zhang, L. Cai, R.W. Wright, L.J. Sandell, M.F. Rai 
Chondroitin sulfate and/or glucosamine hydrochloride for Kashin-Beck disease: a cluster-randomized, placebo-controlled study  J. Yue, M. Yang, S. Yi,
Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis  W.Z. Wang, M.D., Ph.D., X.
N. Takahashi, Ph. D. , K. Rieneck, M. D. , P. M. van der Kraan, Ph. D
D.J. Hunter  Osteoarthritis and Cartilage 
Osteoarthritis year in review 2017: genetics and epigenetics
Y. Kaneko, T. Nozaki, H. Yu, K. Kaneshiro, R. Schwarzkopf, T. Hara, H
Osteoarthritis and Cartilage
S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang 
Novel juvenile factors for cartilage regeneration
Confirmation of two major polyarticular osteoarthritis (POA) phenotypes – differentiation on the basis of joint topography  G.J. Carroll, W.H. Breidahl,
Most patients gain weight in the 2 years after total knee arthroplasty: comparison to a healthy control group  J.A. Zeni, L. Snyder-Mackler  Osteoarthritis.
Location-specific hip joint space width for progression of hip osteoarthritis: predictive validity and responsiveness of a new computerized measure  C.
Imaging biomarker with T1 and T2 mappings in osteoarthritis – In vivo human articular cartilage study  C. Yan, C. Wong, T. Li, N. Gong, Q. Chan, K. Chiu 
Osteoarthritis year 2012 in review: biology
Serum protein signatures detect early radiographic osteoarthritis
K. W. Marshall, M. D. , Ph. D. , F. R. C. S. (C), H. Zhang, M. D. , Ph
M. Doherty, P. Dieppe  Osteoarthritis and Cartilage 
Hypertrophy and structural alterations in tibiofemoral articular cartilage 6-24 months after anterior cruciate ligament reconstruction  E. Thorhauer,
A. Carlson, B. Bothner, R. June  Osteoarthritis and Cartilage 
General Information Osteoarthritis and Cartilage
Long-term effects of vitamin d supplementation and maintaining vitamin d sufficiency on knee osteoarthritis over 5 years  B. Antony, S. Zheng, J. Burgess,
Presentation transcript:

Expression profile of long noncoding rnas in osteoarthritis patients G. Huang, M. Fu, Z. Zhang, J. Liu, Z. Huang, P. Wu, B. Yu, W. Liao  Osteoarthritis and Cartilage  Volume 22, (April 2014) DOI: 10.1016/j.joca.2014.02.445 Copyright © 2014 Terms and Conditions

Fig. 1 Heat Map and Hierarchical Clustering. The result of hierarchical clustering, which was performed based on “Differentially Expressed LncRNAs”, showed distinguishable LncRNAs expression profiling among samples. Osteoarthritis and Cartilage 2014 22, DOI: (10.1016/j.joca.2014.02.445) Copyright © 2014 Terms and Conditions

Fig. 2 The core network of IncRNAs-transcription factor-target genes. Red core presents IncRNA, green core presents transcription factor, orange core presents target gene. Lots of genes targeted by CTCF were predicted as targets genes of these two IncRNAs. Osteoarthritis and Cartilage 2014 22, DOI: (10.1016/j.joca.2014.02.445) Copyright © 2014 Terms and Conditions