What are patients doing with their mosaic embryos

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Presentation transcript:

What are patients doing with their mosaic embryos What are patients doing with their mosaic embryos? Decision making after genetic counseling  Andria G. Besser, M.S., David H. McCulloh, Ph.D., James A. Grifo, M.D., Ph.D.  Fertility and Sterility  Volume 111, Issue 1, Pages 132-137.e1 (January 2019) DOI: 10.1016/j.fertnstert.2018.10.001 Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Initial decisions of patients following genetic counseling about the option of mosaic-embryo transfer. Fertility and Sterility 2019 111, 132-137.e1DOI: (10.1016/j.fertnstert.2018.10.001) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Factors affecting the percentage of patients who elected to pursue mosaic-embryo transfer (MET). (A) Age of patient at the time of counseling. (B) Number of previous egg retrievals. Fertility and Sterility 2019 111, 132-137.e1DOI: (10.1016/j.fertnstert.2018.10.001) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Cumulative temporal distributions for patients who had genetic counseling and those who decided to pursue mosaic-embryo transfer (MET) over the study period. These curves indicate the date of counseling for all patients who completed counseling (blue) and for patients who subsequently elected MET (red). If the percentage of counseled patients who opted for MET was the same throughout the study period, these two curves would be superimposed. From March to May 2016, the rate of rise for patients who elected MET was greater than the rate of rise for patients undergoing counseling, indicating that a higher proportion of counseled patients opted for MET (10/16, 62.5%) during this period. From June 2016 to December 2017, the two curves are relatively parallel, indicating that the percentage of patients who pursued MET following counseling was relatively constant (17/65, 26.2%) during this period. From January to May 2018, the rate of rise for patients who elected MET was less than the rate of rise for patients undergoing genetic counseling, indicating that a smaller percentage of the counseled patients (2/16, 12.5%) pursued MET during this period. Fertility and Sterility 2019 111, 132-137.e1DOI: (10.1016/j.fertnstert.2018.10.001) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions