In vitro effects of antihypertensive drugs on thromboxane agonist (U46619)-induced vasoconstriction in human internal mammary artery Tanaka K.A. , Szlam.

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In vitro effects of antihypertensive drugs on thromboxane agonist (U46619)-induced vasoconstriction in human internal mammary artery Tanaka K.A. , Szlam F. , Katori N. , Tsuda A. , Levy J.H. British Journal of Anaesthesia Volume 93, Issue 2, Pages 257-262 (August 2004) DOI: 10.1093/bja/aeh189 Copyright © 2004 British Journal of Anaesthesia Terms and Conditions

Fig 1 Concentration–response curves for nitroglycerin (n=6), nitroprusside (n=6), and nicardipine (n=7) in human IMA contracted with the TxA2 analogue U46619. Data are expressed as mean (sd), n=number of vessel segments. M=concentration of drugs in mol litre−1. British Journal of Anaesthesia 2004 93, 257-262DOI: (10.1093/bja/aeh189) Copyright © 2004 British Journal of Anaesthesia Terms and Conditions

Fig 2 Concentration–response curves for fenoldopam (n=6) and nicorandil (n=6) in human IMA contracted with the TxA2 analogue U46619. The curve for SNP was also shown as a reference. Data are expressed as mean (sd), n=number of vessel segments. M=concentration of drugs in mol litre−1. British Journal of Anaesthesia 2004 93, 257-262DOI: (10.1093/bja/aeh189) Copyright © 2004 British Journal of Anaesthesia Terms and Conditions

Fig 3 Concentration–response curves for adenosine (n=6) and hydralazine (n=6) in human IMA contracted with the TxA2 analogue U46619. The curve for SNP was also shown as a reference. Data are expressed as mean (sd), n=number of vessel segments. M=concentration of drugs in mol litre−1. British Journal of Anaesthesia 2004 93, 257-262DOI: (10.1093/bja/aeh189) Copyright © 2004 British Journal of Anaesthesia Terms and Conditions

Fig 4 Concentration–response curves for labetalol (n=6), enalaprilat (n=6), and SNP (n=6, reference) in human IMA contracted with the TxA2 analogue U46619. Relaxation response to labetalol (n=5) in human IMA contracted with norepinephrine was also shown (Labetalol-NE). Data are expressed as mean (sd), n=number of vessel segments. M=concentration of drugs in mol litre−1. British Journal of Anaesthesia 2004 93, 257-262DOI: (10.1093/bja/aeh189) Copyright © 2004 British Journal of Anaesthesia Terms and Conditions