Gene Expression Differences between Psoriasis Patients with and without Inflammatory Arthritis  Remy A. Pollock, Fatima Abji, Kun Liang, Vinod Chandran, Fawnda J. Pellett, Carl Virtanen, Dafna D. Gladman  Journal of Investigative Dermatology  Volume 135, Issue 2, Pages 620-623 (February 2015) DOI: 10.1038/jid.2014.414 Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Relationship between the skin and joint disease based on gene expression. Scatter plot of each differentially expressed gene found in PsA versus controls, using the log fold change (FC) values from psoriatic arthritis (PsA) versus cutaneous psoriasis without arthritis (PsC) (joint disease signature) plotted against PsC versus controls (skin disease signature). The majority of genes fall within the first and third quadrants, indicating that genes increased or decreased in PsA relative to PsC are changed in the same direction in PsC relative to controls. Fold changes in PsA versus PsC were typically larger in magnitude compared with fold changes in PsC versus controls, as evidenced by where fold changes fall relative to the diagonal line. Journal of Investigative Dermatology 2015 135, 620-623DOI: (10.1038/jid.2014.414) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions