Safety and Effectiveness of a New Fibrin Pleural Air Leak Sealant: A Multicenter, Controlled, Prospective, Parallel-Group, Randomized Clinical Trial

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Safety and Effectiveness of a New Fibrin Pleural Air Leak Sealant: A Multicenter, Controlled, Prospective, Parallel-Group, Randomized Clinical Trial Alessandro Gonfiotti, MD, Paolo F. Santini, MD, Massimo Jaus, MD, Alberto Janni, MD, PhD, Achille Lococo, MD, PhD, Alessia Raffaella De Massimi, MD, Adolfo D'Agostino, MD, Francesco Carleo, MD, Marco Di Martino, MD, Valentina Larocca, MD, Giuseppe Cardillo, FRCS, FETCS The Annals of Thoracic Surgery Volume 92, Issue 4, Pages 1217-1225 (October 2011) DOI: 10.1016/j.athoracsur.2011.05.104 Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Duration of air leak in hours was compared in patients who underwent treatment with fibrin sealant (FS) and those with standard treatment (ST). The error bars show the standard deviation (SD). FS group: mean, 43.1 (SD, 73.9); ST group: mean, 66.6 (SD, 95.6). *p < 0.005 (Mann-Whitney U test). The Annals of Thoracic Surgery 2011 92, 1217-1225DOI: (10.1016/j.athoracsur.2011.05.104) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Drainage duration in hours was compared in patients who underwent treatment with fibrin sealant (FS) and those with standard treatment (ST). The error bars show the standard deviation (SD). FS group: mean, 143.0 (SD, 74.8). ST group: mean, 157.1 (SD, 129.0). p = 0.992 by Mann-Whitney U test. The Annals of Thoracic Surgery 2011 92, 1217-1225DOI: (10.1016/j.athoracsur.2011.05.104) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions