Elevated cartilage T2 and increased severity of cartilage defects at baseline are associated with the development of knee pain over 7 years G.B. Joseph,

Slides:

Advertisements

Similar presentations

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

Advertisements

Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative M. Hakky, M. Jarraya,

MRI-Based T2 Knee Cartilage Texture Analysis Can Differentiate Subjects With and Without History of Knee Injury Despite Similar Morphological Scores:

Cartilage and meniscal T2 relaxation time as non-invasive biomarker for knee osteoarthritis and cartilage repair procedures T. Baum, G.B. Joseph, D.C.

T1ρ and T2 relaxation times predict progression of knee osteoarthritis

Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral.

Trabecular bone structure and spatial differences in articular cartilage MR relaxation times in individuals with posterior horn medial meniscal tears

Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis.

The relationship between clinical characteristics, radiographic osteoarthritis and 3D bone area: data from the Osteoarthritis Initiative A.J. Barr, B.

A. Bhave, M. Mont, M. Chugthai, R. Starr Osteoarthritis and Cartilage

R. Takeuchi, H. Ishikawa, T. Kuniya, A. Nakazawa

S. Gavard Osteoarthritis and Cartilage

Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST study A. Guermazi,

Prospective economic evaluation of the costs for medications and nutraceuticals in knee osteoarthritis M. Chung, N. Zhao, J.B. Wong, C. Wang Osteoarthritis.

A novel fast knee cartilage segmentation technique for T2 measurements at MR imaging – data from the Osteoarthritis Initiative C. Stehling, T. Baum,

Bone shape does not cause OA – But OA does change bone shape; a study on data from 4654 knees from the Osteoarthritis Initiative M.A. Bowes, C.B. Wolstenholme,

Does a yoga-strengthening program for women with knee osteoarthritis have an effect on gait patterns? An investigation with principal components analysis

Biochemical markers of synovial inflammation – Surrogate markers of synovitis on magnetic resonance imaging? – Data from the osteoarthritis initiative

Quantitatively-measured bone marrow lesions in the patellofemoral joint: distribution and association with pain C. Ratzlaff, R. Russell, J. Duryea Osteoarthritis.

Role of endothelin-1 in endochondral ossification and osteoarthritis

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

M.C. Gallo, V. Pedoia, T.M. Link, R.B. Souza, S. Majumdar

Vastus lateralis/vastus medialis cross-sectional area ratio impacts presence and degree of knee joint abnormalities and cartilage T2 determined with 3T.

Replicability of recommended exercise interventions for knee osteoarthritis: a descriptive systematic review of current clinical guidelines and recommendations

M. K. Javaid, J. A. Lynch, I. Tolstykh, A. Guermazi, F. Roemer, P

Associations between changes in knee pain location and clinical symptoms in people with medial tibiofemoral osteoarthritis: an exploratory study A. Van.

P. Yuan, X. Zhang, W. Yang, W. Kang, B. Yang, J. li, B. Chen, X. Li, B

Variation of radius of curvature around the femoral head and its associations with gender and incident radiographic hip osteoarthritis: Data from the.

Association of ultrasound-defined structural changes with regional and diffuse knee pain patterns – Oulu Knee Osteoarthritis study J. Podlipská, P. Kaukinen,

Pain has a stronger association with thigh muscle strength than the radiographic stage of knee osteoarthritis - data from the Osteoarthritis Initiative

Subjects with higher physical activity levels have more severe focal knee lesions diagnosed with 3T MRI: analysis of a non-symptomatic cohort of the osteoarthritis.

Two different knee braces alter patella position: a moving image analysis using weight bearing magnetic resonance imaging M.J. Callaghan, N.D. Reeves,

The centre of mass trajectory is a sensitive and responsive measure of compensations for pain and weakness among individuals with knee osteoarthritis.

N. Bodick, J. Lufkin, C. Willwerth, A. Kumar, J. Bolognese, C

Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3years –

A new lipid formulation of low dose (1200mg) ibuprofen is non-inferior to high dose (2400mg) standard ibuprofen capsules in managing episodic knee pain.

Do persons with asymmetric hip pain or radiographic hip OA have worse pain and structure outcomes in the knee opposite the more affected hip? Data from.

N. Segal, E. Frick, M. Nevitt, J. Torner, D. Felson, A. Guermazi, D

Quantitative measurement of medial femoral knee cartilage volume – analysis of the OA Biomarkers Consortium FNIH Study cohort L.F. Schaefer, M. Sury,

B. C. Roberts, D. Thewlis, L. B. Solomon, G. Mercer, K. J. Reynolds, E

Differential response of placebo treatments in osteoarthritis trials: a systematic review and network meta-analysis R.R. Bannuru, C.H. Schmid, M.C. Sullivan,

Progression of cartilage damage and meniscal pathology over 30 months is associated with an increase in radiographic tibiofemoral joint space narrowing.

A reference database of cartilage 3 T MRI T2 values in knees without diagnostic evidence of cartilage degeneration: data from the osteoarthritis initiative

Emerging role of endothelin receptor type B in regulating chondrogenic and hypertrophic changes of human mesenchymal stem cells M. Au, M. Zhu, W.-J.

Medial meniscus posterior horn zones show differing responses to static loading in subjects with knee osteoarthritis compared to controls N.E. Calixto,

Racial differences in biochemical knee cartilage composition between African-American and Caucasian-American women with 3 T MR-based T2 relaxation time.

Z. Huang, T. Stabler, F. Pei, V. Kraus Osteoarthritis and Cartilage

A systematic review of the efficacy and general safety of antibodies to NGF in the treatment of OA of the hip or knee T.J. Schnitzer, J.A. Marks Osteoarthritis.

Damps provide a link between joint tissue damage and pain through direct activation of TLR4 expressed by sensory neurons R.E. Miller, P.B. Tran, S. Ishihara,

Low-dose SoluMatrix meloxicam results in clinically meaningful improvements in pain in a phase 3 study of patients with osteoarthritis R. Altman, M.

Evidence for bone mineral density and bone resorption in middle and elderly women with knee osteoarthritis in Shanghai: a cross sectional study Q. Xiaofeng

Walking with increased foot progression angle can reduce joint compression in individuals with knee OA K. Manal, T.S. Buchanan Osteoarthritis and Cartilage

Individuals with severe knee OA are at increased risk of all-cause and cardiovascular disease-specific mortality: The johnston county osteoarthritis project

Subjects with severe knee osteoarthritis reduce medio-lateral forces during gait at the expense of compressive knee contact forces S. Meireles, F. De.

Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study D.K. White, C. Tudor-Locke, Y.

Synovitis and the risk of knee osteoarthritis: the MOST Study

Baseline trabecular bone and its relation to incident radiographic knee osteoarthritis and increase in joint space narrowing score: directional fractal.

Coronal tibial slope is associated with incident accelerated knee osteoarthritis: data from the Osteoarthritis Initiative J.B. Driban, A.C. Stout, J.

Association of hip and pelvic geometry with tibiofemoral osteoarthritis: Multicenter Osteoarthritis Study (MOST) A. Boissonneault, J.A. Lynch, B.L. Wise,

M. Hudelmaier, W. Wirth Osteoarthritis and Cartilage

The association between meniscal damage of the posterior horns and posterior localized synovitis detected on T1-weighted contrast-enhanced MRI: the most.

H. Khan, D. Aitken, C. Ding, L. Blizzard, J. -P. Pelletier, J

Knee kinematic and kinetic modifications under body weight unloading during overground walking at a constant speed A.G. Fischer, E.M. Debbi, A. Wolf

Altered biomechanics and cartilage health changes in bilateral knees following unilateral ACL reconstruction: a 2-year follow-up J.K. Ochoa, K. Amano,

Knee pain outcomes in persons discordant for radiographic hip OA: Data from the osteoarthritis initiative G.B. Joseph, J.F. Hilton, P.M. Jungmann, J.A.

Baseline magnetic resonance imaging cartilage T2 relaxation time measurements as predictors of total knee arthroplasty in African-Americans – Data from.

Longitudinal analysis of cartilage T2 relaxation times and joint degeneration in African American and Caucasian American women over an observation period.

Quantifying biochemical changes in the cartilage matrix in osteoarthritic knee after hyaluronic acid injection using quantitative MR techniques A.R.

General Information Osteoarthritis and Cartilage

Long-term effects of vitamin d supplementation and maintaining vitamin d sufficiency on knee osteoarthritis over 5 years B. Antony, S. Zheng, J. Burgess,

Presentation transcript:

Elevated cartilage T2 and increased severity of cartilage defects at baseline are associated with the development of knee pain over 7 years G.B. Joseph, T. Baum, H. Alizai, L. Nardo, W. Virayavanich, J.A. Lynch, M.C. Nevitt, C.E. McCulloch, T.M. Link Osteoarthritis and Cartilage Volume 21, Pages S185-S186 (April 2013) DOI: 10.1016/j.joca.2013.02.393 Copyright © 2013 Terms and Conditions

Figure 1 Mean baseline cartilage WORMS scores in the lateral femur (lf), lateral tibia (lt), medial femur (mf), medial tibia (mt), and patella (pat) in subjects that did (n = 30) and did not (n = 80) develop pain over 7 years. Osteoarthritis and Cartilage 2013 21, S185-S186DOI: (10.1016/j.joca.2013.02.393) Copyright © 2013 Terms and Conditions