Yaoyu Chen, Jarod Rollins, Beverly Paigen, Xiaosong Wang

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Genetic and Genomic Insights into the Molecular Basis of Atherosclerosis Yaoyu Chen, Jarod Rollins, Beverly Paigen, Xiaosong Wang Cell Metabolism Volume 6, Issue 3, Pages 164-179 (September 2007) DOI: 10.1016/j.cmet.2007.07.001 Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 1 Chromosome Map of Human and Mouse Concordant Quantitative Trait Loci for Atherosclerotic Diseases Human high-density lipoprotein cholesterol (HDL-C) quantitative trait loci (QTLs) are represented by bars to the left of each chromosome. Each bar represents a QTL from one population as shown in Table 1. QTL sizes are given as either 1.5-LOD (logarithm of the odds ratio) drop intervals (if LOD score figures are available) or ±15 cM centered around the LOD score peak (if LOD score figures are unavailable). Human homologs of mouse HDL-C QTLs are represented by red bars to the right of each chromosome, and the chromosome numbers of these mouse QTLs are to their right. Cell Metabolism 2007 6, 164-179DOI: (10.1016/j.cmet.2007.07.001) Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 2 Chromosome Map of Mouse and Human Concordant Atherosclerosis QTLs A vertical black line represents each chromosome, with the centromere at the top. Genetic distances in Mb from the centromere are shown by the scale at the lower left of the figure. Mouse atherosclerosis QTLs are represented by bars to the left of each chromosome. Each bar represents a QTL from one cross as shown in Table 2. QTL sizes are given as 95% confidence intervals (CIs), 1.5-LOD drop intervals (if 95% CIs are not available but LOD score figures are available), or ±10 cM centered around the LOD score peak (if neither CIs nor LOD score figures are available). To change cM into Mb, we found MIT markers at the cM positions in MGI (http://www.informatics.jax.org/) and retrieved their Mb positions from the Ensembl Mouse Genome Server NCBI m36. Mouse homologs of human HDL-C QTLs are represented by red bars to the right of each chromosome, and the chromosome numbers of these human QTLs are to their right. Cell Metabolism 2007 6, 164-179DOI: (10.1016/j.cmet.2007.07.001) Copyright © 2007 Elsevier Inc. Terms and Conditions