Modified Ultrafiltration Versus Conventional Ultrafiltration: A Randomized Prospective Study In Neonatal Piglets C.William Daggett, MD, Andrew J. Lodge,

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Modified Ultrafiltration Versus Conventional Ultrafiltration: A Randomized Prospective Study In Neonatal Piglets C.William Daggett, MD, Andrew J. Lodge, MD, John E. Scarborough, BA, Paul J. Chai, MD, James Jaggers, MD, Ross M. Ungerleider, MD The Journal of Thoracic and Cardiovascular Surgery Volume 115, Issue 2, Pages 336-342 (February 1998) DOI: 10.1016/S0022-5223(98)70277-6 Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 1 CPB circuit with filter. During CPB, tubing clamps are placed at 2 and 3 to exclude the filter. During modified ultrafiltration, tubing clamps are placed at 1 and blood is added from the reservoir through the filter as needed. During conventional ultrafiltration, all tubing clamps are removed. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 336-342DOI: (10.1016/S0022-5223(98)70277-6) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 2 Left ventricle with four microcrystals and microtransducer in place. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 336-342DOI: (10.1016/S0022-5223(98)70277-6) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 3 Total body weight gain after CPB and 120 minutes of recovery. *p < 0.05, MUF versus CUF group and MUF versus control group. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 336-342DOI: (10.1016/S0022-5223(98)70277-6) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 4 Left ventricular wet/dry mass ratios. *p < 0.05, MUF versus CUF group and MUF versus control group. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 336-342DOI: (10.1016/S0022-5223(98)70277-6) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 5 Hematocrit value of piglets during the study period. Only modified ultrafiltration was capable of raising the hematocrit value and maintaining it significantly higher after CPB. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 336-342DOI: (10.1016/S0022-5223(98)70277-6) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 6 Heart rates of piglets during the study as determined by electrocardiographic tracings. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 336-342DOI: (10.1016/S0022-5223(98)70277-6) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 7 Mean arterial pressure as determined by a femoral catheter. *p < 0.01, MUF versus CUF group and MUF versus control group. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 336-342DOI: (10.1016/S0022-5223(98)70277-6) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 8 PRSW determinations of the left ventricle. p < 0.05, MUF versus CUF group and MUF versus control group. The Journal of Thoracic and Cardiovascular Surgery 1998 115, 336-342DOI: (10.1016/S0022-5223(98)70277-6) Copyright © 1998 Mosby, Inc. Terms and Conditions