Amy L. Throckmorton, PhD, James P. Carr, BS, William B

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Presentation transcript:

Uniquely shaped cardiovascular stents enhance the pressure generation of intravascular blood pumps  Amy L. Throckmorton, PhD, James P. Carr, BS, William B. Moskowitz, MD, James J. Gangemi, MD, Christopher M. Haggerty, BS, Ajit P. Yoganathan, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 144, Issue 3, Pages 704-709 (September 2012) DOI: 10.1016/j.jtcvs.2011.12.061 Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Axial flow blood pump and all stent configurations that were hydraulically evaluated. A, Straight filaments without stationary diffuser blades; B, straight filaments with diffuser blades; C, fully twisted filaments with impeller blades and against diffuser blades; D, partial twisted filaments in the direction of the diffuser blades; E, partial twisted filaments against the diffuser blades; F, fully twisted filaments against the impeller blades and with the diffuser blades; G, straight filaments with the diffuser blades extending the full diameter into the vessel; H, filament twist with the impeller blades and diffuser blades; I, filament twist against the impeller blades and against the diffuser blades; J, fully twisted filaments with no diffuser blades; K, partial twist in the filaments and no diffuser blades. In all configurations, except for G, there is a 1.5-mm clearance between the filaments and diffuser blade tip surface. Configuration G has the diffuser blades extended out to the filaments and into the vessel. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 704-709DOI: (10.1016/j.jtcvs.2011.12.061) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Comparison of the numeric predictions to the experimental measurements of the blood pump with a 4-bladed diffuser. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 704-709DOI: (10.1016/j.jtcvs.2011.12.061) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Flow vorticity at 4 axial and cross-sectional locations from the diffuser to the outflow region. A direct comparison of the flow vorticity of the stent configuration with 4 diffuser blades to the configuration without diffuser blades was performed for 3.5 L/min at 6000 RPM. The average vorticity for each location was also predicted for each stent configuration with or without diffuser blades. The 4-bladed diffuser produced the lowest vorticity results compared with the other configurations. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 704-709DOI: (10.1016/j.jtcvs.2011.12.061) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 Regression analysis of the pressure and flow coefficients for each data set to facilitate a quantitative comparison of the results. A, Nondimensionalized hydraulic performance data of the numeric predictions of the stent configuration with a diffuser blade compared with the prototype testing. B, Nondimensionalized hydraulic performance data of the experimental testing of the stent configuration with and without the diffuser blade set. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 704-709DOI: (10.1016/j.jtcvs.2011.12.061) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 Comparison of the regression models of all the protective stent configurations evaluated in the present study. The Journal of Thoracic and Cardiovascular Surgery 2012 144, 704-709DOI: (10.1016/j.jtcvs.2011.12.061) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions