Experimental maternal treatment with dexamethasone during lactation induces neonatal testicular and epididymal oxidative stress; Implications for early.

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Presentation transcript:

Experimental maternal treatment with dexamethasone during lactation induces neonatal testicular and epididymal oxidative stress; Implications for early postnatal exposure S.O. Jeje, F.K. Ola-Mudathir, Y. Raji Pathophysiology Volume 24, Issue 4, Pages 261-265 (December 2017) DOI: 10.1016/j.pathophys.2017.06.002 Copyright © 2017 Elsevier B.V. Terms and Conditions

Fig. 1 SOD activities in testis following maternal dexamethasone treatment during lactation. Values are presented as mean±SEM (n=5). One way Anova revealed that there is a significant difference in the values. (*p<0.05 were significant compared with control) DexLD 1–7 (Dexamethasone exposure at lactation days 1–7) DexLD 1–14 (Dexamethasone exposure at lactation days 1–14) DexLD 1–21 (Dexamethasone exposure at lactation days 1–21) Pathophysiology 2017 24, 261-265DOI: (10.1016/j.pathophys.2017.06.002) Copyright © 2017 Elsevier B.V. Terms and Conditions

Fig. 2 SOD activities in epididymis following maternal dexamethasone treatment during lactation. Values are presented as mean±SEM (n=5). One way Anova revealed that there is a significant difference in the values. (*p<0.05 were significant compared with control) DexLD 1–7 (Dexamethasone exposure at lactation days 1–7) DexLD 1–14 (Dexamethasone exposure at lactation days 1–14) DexLD 1–21 (Dexamethasone exposure at lactation days 1–21) Pathophysiology 2017 24, 261-265DOI: (10.1016/j.pathophys.2017.06.002) Copyright © 2017 Elsevier B.V. Terms and Conditions

Fig. 3 Catalase activities in testis following maternal dexamethasone treatment during lactation. Values are presented as mean±SEM (n=5), One way Anova revealed that there is a significant difference in the values. (*p<0.05 were significant compared with control) DexLD 1–7 (Dexamethasone exposure at lactation days 1k7) DexLD 1–14 (Dexamethasone exposure at lactation days 1–14) DexLD 1–21 (Dexamethasone exposure at lactation days 1–21) Pathophysiology 2017 24, 261-265DOI: (10.1016/j.pathophys.2017.06.002) Copyright © 2017 Elsevier B.V. Terms and Conditions

Fig. 4 Catalase activities in epididymis following maternal dexamethasone treatment during lactation. Values are presented as mean±SEM (n=5), One way Anova revealed that there is a significant difference in the values. (*p<0.05 were significant compared with control) DexLD 1–7 (Dexamethasone exposure at lactation days 1–7) DexLD 1–14 (Dexamethasone exposure at lactation days 1–14) DexLD 1–21 (Dexamethasone exposure at lactation days 1–21) Pathophysiology 2017 24, 261-265DOI: (10.1016/j.pathophys.2017.06.002) Copyright © 2017 Elsevier B.V. Terms and Conditions