Neonate, 4 days. Neonate, 4 days. Sagittal SE T1-weighted MR image (600/8/2) shows white matter anomalies as punctate hyperintensities (two marked by long.

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MR images of cytoarchitectural dysplasia

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Axial T1-weighted image after contrast administration (A) and a FLAIR image (B) demonstrating a left parietal subcortical DVA with deep venous drainage.

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Supratentorial and posterior fossa PML

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Sagittal T1-weighted MR image of the pituitary gland in a preterm neonate (born at gestational week 28) obtained near term (corrected age of 39 weeks;

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Axial T2-weighted image (A) demonstrates focal cortical dysplasia (arrow) centered in the left anterior temporal lobe in a right-handed patient. Axial.

ALD in an 8-year-old patient.

Sagittal MPRAGE (A) and axial T2-weighted (B) images demonstrate extensive focal cortical dysplasia (arrow) involving most of the visualized left frontal.

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Axial fluid-attenuated inversion recovery MR of same patient as in Fig 1 done 19 days later (patient remained hospitalized) now showing an isointense area.

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Marked progression of PML documented by serial MR studies

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Presentation transcript:

Neonate, 4 days. Neonate, 4 days. Sagittal SE T1-weighted MR image (600/8/2) shows white matter anomalies as punctate hyperintensities (two marked by long arrows) radiating toward ventricles, several subependymal nodules (one marked by curved arrow) in left atrium, and incidental postnatal findings of hyperintense subdural hemorrhage overlying cerebellum and parietal caput succedaneum (not marked).fig 2. Neonate, 7 days.A, Sagittal SE T1-weighted MR image (600/15/2) shows left-hemispheric large transmantle dysplasia (short arrows) as hyperintense area extending from frontoparietal cortex to lateral ventricle; bright subependymal nodules (two marked by curved arrows), located around atrium and temporal horn; and parietal hyperintense linear white matter anomalies (long arrow).B, Axial SE T1-weighted MR image (500/15/2) shows transmantle dysplasia (short arrows) underlying asymmetrically large perisylvian subarachnoid space; hyperintense probable SGCA (>12 mm) is seen at right foramen of Monro (curved arrow) and subependymal nodules at left foramen of Monro and atrium (only atrium marked, long arrow). Yvonne Baron, and A. James Barkovich AJNR Am J Neuroradiol 1999;20:907-916 ©1999 by American Society of Neuroradiology