Impact of Donor and Recipient Cytomegalovirus Serostatus on Outcomes of Antithymocyte Globulin–Conditioned Hematopoietic Cell Transplantation  Amit Kalra,

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Presentation transcript:

Impact of Donor and Recipient Cytomegalovirus Serostatus on Outcomes of Antithymocyte Globulin–Conditioned Hematopoietic Cell Transplantation  Amit Kalra, Tyler Williamson, Andrew Daly, M. Lynn Savoie, Douglas A. Stewart, Faisal Khan, Jan Storek  Biology of Blood and Marrow Transplantation  Volume 22, Issue 9, Pages 1654-1663 (September 2016) DOI: 10.1016/j.bbmt.2016.05.020 Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 OS, RFS, cumulative incidence of relapse mortality, and NRM in CMV-seropositive recipients (R+) and CMV-seronegative recipients (R−) irrespective of donor CMV serostatus. The P values are from multivariate analyses. Biology of Blood and Marrow Transplantation 2016 22, 1654-1663DOI: (10.1016/j.bbmt.2016.05.020) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 OS, RFS, cumulative incidence of relapse, and NRM in CMV-seronegative recipients by donor CMV serostatus. The P values are from multivariate analyses. Biology of Blood and Marrow Transplantation 2016 22, 1654-1663DOI: (10.1016/j.bbmt.2016.05.020) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 OS, RFS, cumulative incidence of relapse, and NRM in patients by CMV serostatus of donor and recipient. The P values shown are for the comparison of the donor CMV-seronegative and recipient CMV-seropositive group (D−R+) with the donor CMV-seropositive and recipient CMV-seropositive group (D+R+). The P values are from multivariate analyses. NS, not significant. Biology of Blood and Marrow Transplantation 2016 22, 1654-1663DOI: (10.1016/j.bbmt.2016.05.020) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 OS, RFS, cumulative incidence of relapse, and NRM in CMV-seropositive recipients grouped according to donor CMV serostatus and donor type (HLA-matched sibling versus 8/8 HLA allele–matched unrelated donor). The P values shown are for the comparison of the D−R+ matched sibling group with the D+R+ matched unrelated donor group, and are from multivariate analyses. Biology of Blood and Marrow Transplantation 2016 22, 1654-1663DOI: (10.1016/j.bbmt.2016.05.020) Copyright © 2016 American Society for Blood and Marrow Transplantation Terms and Conditions