DNA Made of Purines Only

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DNA Made of Purines Only Christoph Arenz, Oliver Seitz Chemistry & Biology Volume 14, Issue 5, Pages 467-469 (May 2007) DOI: 10.1016/j.chembiol.2007.05.001 Copyright © 2007 Elsevier Ltd Terms and Conditions

Figure 1 Enlarged Watson-Crick Base Pairs (A) In naturally occurring DNA, purines form Watson-Crick base pairs with pyrimidines. (B) In Eschenmoser's linear homoDNA [8] the purines 2,6-diaminopurine (D) and guanine (G) can pair with the purines xanthine (X) and isoguanine (I) in a Watson-Crick fashion. (C) Size-expanded Watson-Crick base pairs in helical DNA duplexes have been shown by Kool [10]. (D) In this issue, Battersby and colleagues introduce purine-purine pairing as an alternative mode of DNA duplex association between components that all occur in nature. Chemistry & Biology 2007 14, 467-469DOI: (10.1016/j.chembiol.2007.05.001) Copyright © 2007 Elsevier Ltd Terms and Conditions