Oxygen regulates lipid profiles in human primary chondrocyte cultures

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Presentation transcript:

Oxygen regulates lipid profiles in human primary chondrocyte cultures B. Bakker, G.B. Eijkel, R.M. Heeren, M. Karperien, J.N. Post, B. Cillero-Pastor Osteoarthritis and Cartilage Volume 24, Pages S456-S457 (April 2016) DOI: 10.1016/j.joca.2016.01.833 Copyright © 2016 Terms and Conditions

Figure 1. Spectral mapping of positive (A) and negative (B) lipid ions in chondrocyte pellets cultured in normoxia (DF1+) and hypoxia (DF1-).DF:Discriminant function, PC: phosphatidylcholine, SM: sphingomyelin, PG: phosphatidylglycerol and PI: phosphatidylinositol, PS: phosphatidylserine, m/z= mass/charge. Osteoarthritis and Cartilage 2016 24, S456-S457DOI: (10.1016/j.joca.2016.01.833) Copyright © 2016 Terms and Conditions

Figure 2. Lipid distribution and presence in chondrocyte pellets Figure 2. Lipid distribution and presence in chondrocyte pellets.Sphingomyelin dl8:l/16:0 (m/z 741.5) expression is higher in hypoxic pellets and phosphatidylcholine 18:0/18:1 (m/z 810.6) is higher in normoxic pellets. Osteoarthritis and Cartilage 2016 24, S456-S457DOI: (10.1016/j.joca.2016.01.833) Copyright © 2016 Terms and Conditions