Selection of embryos for transfer in IVF: ranking embryos based on their implantation potential using morphological scoring  Laura van Loendersloot, Madelon.

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Presentation transcript:

Selection of embryos for transfer in IVF: ranking embryos based on their implantation potential using morphological scoring  Laura van Loendersloot, Madelon van Wely, Fulco van der Veen, Patrick Bossuyt, Sjoerd Repping  Reproductive BioMedicine Online  Volume 29, Issue 2, Pages 222-230 (August 2014) DOI: 10.1016/j.rbmo.2014.04.016 Copyright © 2014 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Distribution of the calculated probabilities in the development set and validation set with traceable embryos. (A) Development set. (B) Validation set. Reproductive BioMedicine Online 2014 29, 222-230DOI: (10.1016/j.rbmo.2014.04.016) Copyright © 2014 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Calibration plots showing associations between calculated and observed ongoing embryo implantation rates. (A) Development set with traceable embryos. (B) Validation set with traceable embryos. (C) Validation of complete development set. (D) Validation of complete validation set. To calculate the actual implantation rate (IR) for panels A and B, the calculated probabilities for the development and validation sets need to be corrected with a factor 1.9 (IR in total data set / IR in development set = 1.9). (A) Corrected calculated probabilities of an ongoing implantation ranged from 0.00 to 0.39 (mean 0.14). (B) Corrected calculated probabilities of an ongoing implantation ranged from 0.00 to 0.39 (mean 0.14). (C and D) These are the corrected calculated probabilities. Reproductive BioMedicine Online 2014 29, 222-230DOI: (10.1016/j.rbmo.2014.04.016) Copyright © 2014 Reproductive Healthcare Ltd. Terms and Conditions

Reproductive BioMedicine Online 2014 29, 222-230DOI: (10. 1016/j. rbmo Copyright © 2014 Reproductive Healthcare Ltd. Terms and Conditions