Preoperative versus Postoperative Chemotherapy in Patients with Resectable Non- small Cell Lung Cancer: Systematic Review and Indirect Comparison Meta-Analysis.

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Presentation transcript:

Preoperative versus Postoperative Chemotherapy in Patients with Resectable Non- small Cell Lung Cancer: Systematic Review and Indirect Comparison Meta-Analysis of Randomized Trials Eric Lim, MB, ChB, MD, MSc, FRCS, Grace Harris, MBBS, Amit Patel, MB, ChB, MRCS, Iki Adachi, MD, Lyn Edmonds, MCLIP, Fujian Song, BMed, MMed, PhD Journal of Thoracic Oncology Volume 4, Issue 11, Pages 1380-1388 (November 2009) DOI: 10.1097/JTO.0b013e3181b9ecca Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Quality of reporting of meta-analyses flow diagram. Journal of Thoracic Oncology 2009 4, 1380-1388DOI: (10.1097/JTO.0b013e3181b9ecca) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Forrest plot of overall survival comparing chemotherapy to control. Journal of Thoracic Oncology 2009 4, 1380-1388DOI: (10.1097/JTO.0b013e3181b9ecca) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Cumulative data meta-analysis of preoperative chemotherapy trials. Journal of Thoracic Oncology 2009 4, 1380-1388DOI: (10.1097/JTO.0b013e3181b9ecca) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Cumulative data meta-analysis of postoperative chemotherapy trials. Journal of Thoracic Oncology 2009 4, 1380-1388DOI: (10.1097/JTO.0b013e3181b9ecca) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions