Development of an intraluminal device for the treatment of aortic regurgitation: Prototype and in vitro testing system Robert C. Ashton, MDc, Daniel.

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Presentation transcript:

Development of an intraluminal device for the treatment of aortic regurgitation: Prototype and in vitro testing system Robert C. Ashton, MDc, Daniel J. Goldstein, MDa, David D'Alessandro, BSa, Alan D. Weinberg, MSa, Daniel Burkhoff, MD b, Heinz D. Rosskothena, Gerald M. Lemole, MDd, Mehmet C. Oz, MDa The Journal of Thoracic and Cardiovascular Surgery Volume 112, Issue 4, Pages 979-983 (October 1996) DOI: 10.1016/S0022-5223(96)70098-3 Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 1 Mock circulatory loop system used to test aortic valves. This system simulates physiologic pressure-flow characteristics of normal human arterial system. 1, Pulsatile ventricular-assist device (Abiomed BVS 5000). 2, Housing chamber for human aortic valves and obturator. 3, Flow probe to measure flows through system. 4, Capacitance chamber 1 to aid in regulation of pressure. 5, Capacitance chamber 2 to aid in regulation of pressure. 6, Resistance element to create diastolic pressure. 7, Fluid reservoir of system. 8, Console of ventricular-assist device to simulate normal heart function. 9, Computer and MacLab to record pressures and flows within system. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 979-983DOI: (10.1016/S0022-5223(96)70098-3) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 2 Housing chamber for aortic valves. This chamber is composed of acrylic and consists of inflow and outflow conduits through which transducers measure pressure on each side of aortic valve. Obturator is introduced through top of this chamber, and valves are situated in sleeves within chamber. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 979-983DOI: (10.1016/S0022-5223(96)70098-3) Copyright © 1996 Mosby, Inc. Terms and Conditions

Fig. 3 Aortic valve obturators. 1, Solid ball. 2, Solid diamond. 3, Solid pyramid with straight sides. 4, Solid pyramid with concave sides. 5, Hollow pyramid with straight sides. 6, Hollow pyramid with concave sides. The Journal of Thoracic and Cardiovascular Surgery 1996 112, 979-983DOI: (10.1016/S0022-5223(96)70098-3) Copyright © 1996 Mosby, Inc. Terms and Conditions