Figure 2 Light microscopy images of brain autopsy case II-2

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Figure 3 Brain MRI findings in patients with MOG-Ab Extensive brain lesions with large diameter (A and B), posterior reversible encephalopathy–like lesions.

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Figure 2 Neuropathologic examination for lymphoma etiology (patients 1–4)‏ Neuropathologic examination for lymphoma etiology (patients 1–4) Immunohistochemical.

Figure 3 Complete loss of neurofilament light (NEFL) protein in cultured patient neurons Complete loss of neurofilament light (NEFL) protein in cultured.

Figure 5 Increased frequency of parenchymal CD138- and LMP-1–positive cells in MS Increased frequency of parenchymal CD138- and LMP-1–positive cells in.

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Figure 2 Light microscopy images of brain autopsy case II-2 Light microscopy images of brain autopsy case II-2 Frontal cortex (area 8). (A) Swollen neuronal perikarya and the proximal part of the axons (arrows). (B) Age-matched control case. (C) Dilated proximal axons filled with lipopigmentary granules (arrows). (D) Similar picture showing immunoreactivity for cathepsin D (arrows). (E) Autofluorescence of the lipopigmentary granules. (F) Periodic acid-Schiff positivity of the stored granules (arrows). Paraffin sections; A and C: Klüver-Barrera staining, B: cresyl violet, D: antibody against cathepsin D, E: autofluorescence, F: Periodic acid-Schiff method; scale = 50 μm. Julie van der Zee et al. Neurol Genet 2016;2:e102 © 2016 American Academy of Neurology