Cell cycle: Driving the centrosome cycle

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Cell cycle: Driving the centrosome cycle Mark Winey  Current Biology  Volume 9, Issue 12, Pages R449-R452 (June 1999) DOI: 10.1016/S0960-9822(99)80279-6

Figure 1 Studies using centrosome reduplication systems have recently provided evidence that Cdk2–cyclin E is necessary for centrosome duplication [6][7][8]. (See text for details.) Current Biology 1999 9, R449-R452DOI: (10.1016/S0960-9822(99)80279-6)

Figure 2 Spindle pole duplication in various organisms and the dependency of these duplication events on various cyclin-dependent kinases. (a) The vertebrate centrosome under the control of Cdk2–cyclin E [6][7][8]. (b) The budding yeast spindle pole body under the control of Cdc28–Clns [13]. (c) The fission yeast spindle pole body duplication [14] under, it is presumed, the control of the Cdc2–Cdc13. Current Biology 1999 9, R449-R452DOI: (10.1016/S0960-9822(99)80279-6)