A new method of sweat testing: the CF Quantum®sweat test

Slides:



Advertisements
Similar presentations
Comparing age of cystic fibrosis diagnosis and treatment initiation after newborn screening with two common strategies  Don B. Sanders, Huichuan J. Lai,
Advertisements

Treatment compliance in children and adults with Cystic Fibrosis
Cystic fibrosis-related bone disease in children: Examination of peripheral quantitative computed tomography (pQCT) data  Denise S.K. Brookes, Julie N.
Long-term follow-up of cystic fibrosis newborn screening: Psychosocial functioning of adolescents and young adults  Audrey Tluczek, Anita Laxova, Adam.
Cystic Fibrosis Screen Positive, Inconclusive Diagnosis (CFSPID): A new designation and management recommendations for infants with an inconclusive diagnosis.
Sweat conductivity: An accurate diagnostic test for cystic fibrosis?
Zachary M. Sellers, Lori McGlocklin, Andrea Brasch 
Towards an individualized protocol for workload increments in cardiopulmonary exercise testing in children and adolescents with cystic fibrosis  H.J.
GFR estimates using cystatin C are superior to serum creatinine in adult patients with cystic fibrosis  Paul M. Beringer, Levita Hidayat, Anna Heed, Ling.
How does heart rate recovery after sub-maximal exercise correlate with maximal exercise testing in children with CF?  Sarah P. Cohen, David M. Orenstein 
Megan R. Nelson, Craig R. Adamski, Audrey Tluczek 
Amoxicillin–clavulanic acid resistance in fecal Enterobacteriaceae from patients with cystic fibrosis and healthy siblings  Gwen Duytschaever, Geert Huys,
Urinary incontinence in 9���16��year olds with cystic fibrosis compared to other respiratory conditions and a normal group  W.J. Browne, C.J. Wood, M.
Nadav Traeger, Qiuhu Shi, Allen J. Dozor  Journal of Cystic Fibrosis 
Measures of body habitus are associated with lung function in adults with cystic fibrosis: A population-based study  Doug L. Forrester, Alan J. Knox,
Microbiological yield from induced sputum compared to oropharyngeal swab in young children with cystic fibrosis  Marco Zampoli, Komala Pillay, Henri Carrara,
Laura Viviani, Baroukh M. Assael, Eitan Kerem 
Cirrhosis and other liver disease in cystic fibrosis
Katelyn Krivchenia, Don Hayes, Joseph D. Tobias, Dmitry Tumin 
The ease of breathing test tracks clinical changes in cystic fibrosis
Rate of improvement of CF life expectancy exceeds that of general population— Observational death registration study  Matthew N. Hurley, Tricia M. McKeever,
Controlled clinical trials in cystic fibrosis — are we doing better?
Anju Anand, Elizabeth Tullis, Anne Stephenson, Preyanka Abhyankar 
D. Stevens, P.J. Oades, N. Armstrong, C.A. Williams 
Claire J. Tipping, Rebecca L. Scholes, Narelle S. Cox 
Cystic fibrosis mortality trend in Italy from 1970 to 2011
Vitamin A and lung function in CF
The predictive potential of the sweat chloride test in cystic fibrosis patients with the G551D mutation  Verena I. Seliger, David Rodman, Fredrick Van.
Abnormal electrochemical skin conductance in cystic fibrosis
A.H. Gifford  Journal of Cystic Fibrosis 
Agreement of bioelectric impedance analysis and dual-energy X-ray absorptiometry for body composition evaluation in adults with cystic fibrosis  S. Ziai,
Inhalation solutions — Which ones may be mixed
Physiologic endpoints for clinical studies for cystic fibrosis
Antonia V. Bennett, Donald L. Patrick, James F. Lymp, Todd C
Correlation of sweat chloride and percent predicted FEV1 in cystic fibrosis patients treated with ivacaftor  Meredith C. Fidler, Jack Beusmans, Paul Panorchan,
E. Tschiedel, H. Grasemann, F. Ratjen  Journal of Cystic Fibrosis 
Colon Cancer in Cystic Fibrosis patients: Is this a growing problem?
Depression and anxiety in adolescents and adults with cystic fibrosis in the UK: A cross- sectional study  Alistair J.A. Duff, Janice Abbott, Carolyn Cowperthwaite,
Sally H. Pattison, Geraint B. Rogers, Martin Crockard, J
Prevalence and risk factors for recovery of filamentous fungi in individuals with cystic fibrosis  Christopher R. Sudfeld, Elliott C. Dasenbrook, William.
Marie-Angela Schnyder, Christian Benden, Christoph Schmid 
Stenotrophomonas maltophilia in cystic fibrosis: Improved detection by the use of selective agar and evaluation of antimicrobial resistance  P. Goncalves-Vidigal,
Nasal polyposis in lung transplant recipients with cystic fibrosis
Narelle S. Cox, Jennifer Follett, Karen O. McKay 
Novel concepts in evaluating antimicrobial therapy for bacterial lung infections in patients with cystic fibrosis  Geraint B. Rogers, Lucas R. Hoffman,
Nutritional decline in cystic fibrosis related diabetes: The effect of intensive nutritional intervention  H. White, K. Pollard, C. Etherington, I. Clifton,
Chronic Stenotrophomonas maltophilia infection and mortality or lung transplantation in cystic fibrosis patients  Valerie Waters, Eshetu G. Atenafu, Annie.
Gender differences in treatment adherence among youth with cystic fibrosis: Development of a new questionnaire  Joän M. Patterson, Melanie Wall, Jerica.
Disease disclosure in individuals with cystic fibrosis: Association with psychosocial and health outcomes  Adrienne P. Borschuk, Robin S. Everhart, Michelle.
Trends in pathogens colonising the respiratory tract of adult patients with cystic fibrosis, 1985–2005  F.A. Millar, N.J. Simmonds, M.E. Hodson  Journal.
F. Vermeulen, P. Lebecque, K. De Boeck, T. Leal 
Successful treatment of cepacia syndrome with a combination of intravenous cyclosporin, antibiotics and oral corticosteroids  Francis J. Gilchrist, A.
V. Thompson, N. Mayer-Hamblett, M. Kloster, D. Bilton, P.A. Flume 
Stability of interleukin 8 and neutrophil elastase in bronchoalveolar lavage fluid following long-term storage  Luke J. Berry, Barbara Sheil, Luke Garratt,
Comparing age of cystic fibrosis diagnosis and treatment initiation after newborn screening with two common strategies  Don B. Sanders, Huichuan J. Lai,
Modification of the salivary secretion assay in F508del mice — The murine equivalent of the human sweat test  Karoline Droebner, Peter Sandner  Journal.
J.E. Spahr, R.B. Love, M. Francois, K. Radford, K.C. Meyer 
Daniel J. Smith, Gregory J. Anderson, Scott C. Bell, David W. Reid 
Michael W. Konstan, David J. Pasta, Jeffrey S. Wagener, Donald R
V. Terlizzi, A. Tosco, R. Tomaiuolo, A. Sepe, N. Amato, A. Casale, C
Gut dysbiosis in cystic fibrosis
CFTR modulators and pregnancy: Our work has only just begun
‘Peeling paint’ dermatitis as a presenting sign of cystic fibrosis
Beta-lactam allergy in adults with cystic fibrosis
Michael W. Konstan, Jeffrey S. Wagener, Donald R. VanDevanter, David J
Lutz Goldbeck, Sven Zerrer, Tim G. Schmitz  Journal of Cystic Fibrosis 
Khin M. Gyi, Margaret E. Hodson, Magdi Y. Yacoub 
David Adeboyeku, Sandra Scott, Margaret E. Hodson 
Elisabeth P. Dellon, Margaret W. Leigh, James R. Yankaskas, Terry L
Anne K. Swisher, Kathryn Moffett, Linda Baer 
Presentation transcript:

A new method of sweat testing: the CF Quantum®sweat test Michael J. Rock, Linda Makholm, Jens Eickhoff  Journal of Cystic Fibrosis  Volume 13, Issue 5, Pages 520-527 (September 2014) DOI: 10.1016/j.jcf.2014.05.001 Copyright © 2014 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 Electrode and controller set on a child’s arm. Journal of Cystic Fibrosis 2014 13, 520-527DOI: (10.1016/j.jcf.2014.05.001) Copyright © 2014 European Cystic Fibrosis Society. Terms and Conditions

Fig. 2 CFQT patches: on left, sweat chloride of 16mmol/L; on right, sweat chloride of 83mmol/L (as measured by CF analyzer). Journal of Cystic Fibrosis 2014 13, 520-527DOI: (10.1016/j.jcf.2014.05.001) Copyright © 2014 European Cystic Fibrosis Society. Terms and Conditions

Fig. 3 CFQT results against conventional sweat test results. Solid line, regression line. Shaded area, intermediate sweat chloride values. Journal of Cystic Fibrosis 2014 13, 520-527DOI: (10.1016/j.jcf.2014.05.001) Copyright © 2014 European Cystic Fibrosis Society. Terms and Conditions

Fig. 4 Bland–Altman plot of differences between CFQT and conventional sweat chloride versus their average. Solid line, mean difference; dotted lines, mean difference±1.96 SD. Journal of Cystic Fibrosis 2014 13, 520-527DOI: (10.1016/j.jcf.2014.05.001) Copyright © 2014 European Cystic Fibrosis Society. Terms and Conditions