Telomeres: The Molecular Events Driving End-To-End Fusions

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Telomeres: The Molecular Events Driving End-To-End Fusions Alison A Bertuch  Current Biology  Volume 12, Issue 21, Pages R738-R740 (October 2002) DOI: 10.1016/S0960-9822(02)01252-6

Figure 1 Chromosomal products of NHEJ of dysfunctional telomeres. At the top is illustrated the consequences of NHEJ of dysfunctional telomeres following DNA synthesis; sister and non-sister chromatid type fusions are observed on metaphase spreads. At the bottom is shown the generation of chromosome type fusions as a consequence of fusion of dysfunctional telomeres prior to DNA replication. Current Biology 2002 12, R738-R740DOI: (10.1016/S0960-9822(02)01252-6)