Heart-Type Fatty Acid Binding Protein and Ischemia-Modified Albumin for Detection of Myocardial Infarction After Coronary Artery Bypass Graft Surgery

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Heart-Type Fatty Acid Binding Protein and Ischemia-Modified Albumin for Detection of Myocardial Infarction After Coronary Artery Bypass Graft Surgery Matthias Thielmann, MD, PhD, Susanne Pasa, MD, Torulv Holst, MD, Daniel Wendt, MD, PhD, Daniel-Sebastian Dohle, MD, Ender Demircioglu, MD, Vikram Sharma, MD, Heinz Jakob, MD, PhD The Annals of Thoracic Surgery Volume 104, Issue 1, Pages 130-137 (July 2017) DOI: 10.1016/j.athoracsur.2016.10.051 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Study protocol. (CABG = coronary artery bypass graft surgery; cTnI = cardiac troponin I; ECG = electrocardiogram; h = hour; hFABP = heart-type fatty acid binding protein; IMA = ischemia-modified albumin; PMI = perioperative myocardial infarction.) The Annals of Thoracic Surgery 2017 104, 130-137DOI: (10.1016/j.athoracsur.2016.10.051) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Cohort A. Mean serum levels (±SD) of (A) cardiac troponin I (cTnI) and (B) heart-type fatty acid binding protein (hFABP) with perioperative myocardial infarction (black line) and without perioperative myocardial infarction (gray line) at baseline, and at 1, 6, 12, 24, 48, and 72 hours after coronary artery bypass graft surgery (CABG). Asterisk (*) indicates p < 0.001 versus control (two-way analysis of variance). (ANOVA = analysis of variance; PMI = perioperative myocardial infarction.) The Annals of Thoracic Surgery 2017 104, 130-137DOI: (10.1016/j.athoracsur.2016.10.051) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Cohort B. Mean serum levels (±SD) of (A) cardiac troponin I (cTnI) and (B) ischemia-modified albumin (IMA) with perioperative myocardial infarction (black line) and without perioperative myocardial infarction (gray line) at baseline, and at 1, 6, 12, 24, 48, and 72 hours after coronary artery bypass graft surgery (CABG). Asterisk (*) indicates p < 0.001 versus control (two-way analysis of variance). (ANOVA = analysis of variance; PMI = perioperative myocardial infarction.) The Annals of Thoracic Surgery 2017 104, 130-137DOI: (10.1016/j.athoracsur.2016.10.051) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions