Effect of a Carbonaceous Oral Adsorbent on the Progression of CKD: A Multicenter, Randomized, Controlled Trial Tadao Akizawa, MD, PhD, Yasushi Asano,

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Effect of a Carbonaceous Oral Adsorbent on the Progression of CKD: A Multicenter, Randomized, Controlled Trial Tadao Akizawa, MD, PhD, Yasushi Asano, MD, PhD, Satoshi Morita, PhD, Takafumi Wakita, MS, Yoshihiro Onishi, PhD, MPH, Shunichi Fukuhara, MD, DMSc, Fumitake Gejyo, MD, PhD, Seiichi Matsuo, MD, PhD, Noriaki Yorioka, MD, PhD, Kiyoshi Kurokawa, MD American Journal of Kidney Diseases Volume 54, Issue 3, Pages 459-467 (September 2009) DOI: 10.1053/j.ajkd.2009.05.011 Copyright © 2009 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Carbonaceous Oral Adsorbent's Effects on Progression of Chronic Kidney Disease (CAP-KD) participant flow chart. American Journal of Kidney Diseases 2009 54, 459-467DOI: (10.1053/j.ajkd.2009.05.011) Copyright © 2009 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Length of survival before reaching the primary end point, by treatment group. Short vertical tick marks indicate censored data. The difference between groups was not statistically significant (P = 0.9, log-rank test). American Journal of Kidney Diseases 2009 54, 459-467DOI: (10.1053/j.ajkd.2009.05.011) Copyright © 2009 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Estimated glomerular filtration rate (eGFR; estimated as described in Matsuo et al18) over time, by treatment group. Vertical lines indicate 95% confidence intervals. American Journal of Kidney Diseases 2009 54, 459-467DOI: (10.1053/j.ajkd.2009.05.011) Copyright © 2009 National Kidney Foundation, Inc. Terms and Conditions