On the exact distribution of the numbers of alleles in DNA mixtures

Slides:

Advertisements

Similar presentations

The most efficient STR loci in forensic genetics in population of central Poland R. Jacewicz, M. Jedrzejczyk, J. Berent Forensic Science International:

Advertisements

A comparison of AmpFlSTR Identifiler™ Kit versus AmpFlSTR Identifiler Plus™ Kit in challenging bone samples by using normal and increased PCR cycle number

B. Szkuta, M.L. Harvey, K.N. Ballantyne, R.A.H. van Oorschot

A comparison of AmpFlSTR Identifiler™ Kit versus AmpFlSTR Identifiler Plus™ Kit in challenging bone samples by using normal and increased PCR cycle number

T. Tamura, M. Osawa, Y. Inaoka, S. Tanaka, F. Satoh, T. Nakamura

A. Verzeletti, V. Cortellini, S. Cisana, S. Pretto, N. Cerri, F

Use of matrix standards for new fluorophores in capillary sequencers

R. Alghafri, W. Goodwin, S. Hadi

Statistical model for degraded DNA samples and adjusted probabilities for allelic dropout Torben Tvedebrink, Poul Svante Eriksen, Helle Smidt Mogensen,

A priori probabilities in Y23 mixture analysis: Non-contributor experiments using simulated powerplex® Y23 Y-STR mixtures D. Moore, T. Clayton, J. Thomson

Performance of the RapidHIT™200

A. Barbaro, P. Cormaci, G. Falcone

Use of universal reporter primers in multiplex PCR of autosomal loci

Modelling noise in second generation sequencing forensic genetics STR data using a one-inflated (zero-truncated) negative binomial model Søren B. Vilsen,

Characterization of mutations and sequence variations in complex STR loci by second generation sequencing Sigrun Dalsgaard, Eszter Rockenbauer, Chiara.

Probabilistic modelling for DNA mixture analysis

C. Davies, J. Thomson, F. Kennedy

Study of two X-linked microsatellite blocks: Allelic frequencies in mixed and isolated population groups M. Castañeda, A. Odriozola, V. Mijares, M.T.

The effect of increased cycle numbers using the Quantifiler® Duo DNA Quantification Kit (AB) on the detection of minute amounts of male DNA in mixtures.

DNA typing of trace DNA recovered from different areas of sandals found at a homicide crime scene investigation: A comparative study Samuel T.G. Ferreira,

Juliana G. Aquino, Juliana Jannuzzi, Elizeu F. Carvalho, Leonor Gusmão

Development and use of a single-tube four dye, 21plex direct PCR autosomal STR loci amplification assay for human identification and relationship testing

Establishment of Italian national DNA database and the central laboratory: Some aspects R. Biondo, F. De Stefano Forensic Science International: Genetics.

U. Ricci, I. Carboni, S. Iozzi, A. Gozzini, F. Torricelli

Population data for SE33 locus in United Arab Emirates Arab population

Christel H. Petersen, Benjamin B. Hjort, Torben Tvedebrink, Lukasz J

New set of markers for individual geographic origin

A rape case with multiple unknown perpetrators

Automated extraction of DNA from clothing

Combining DNA evidence for greater match information

Oskar Hansson, Peter Gill

A. Verzeletti, V. Cortellini, S. Cisana, S. Pretto, N. Cerri, F

Body fluid mixtures: Resolution using forensic microRNA analysis

Evaluation of GeneMapper®ID-X Mixture Analysis tool

Denilce R. Sumita, Martin R. Whittle

Evaluating DNA profiles using peak heights, allowing for dropin, dropout and stutters Roberto Puch-Solis Forensic Science International: Genetics Supplement.

Joanne L. Simons, Amelia Gamblin, Laura Arnold, Sue C. Vintiner

M. Omedei, C. Martino, S. Gino

Quadruplex real-time PCR for forensic DNA quantitation

Multiplex DNA amplification and barcoding in a single reaction for 454 Roche sequencing: A comprehensive study on the control region of the mitochondrial.

New RNA methods for the identification of body fluids and cell types

A review of low template STR analysis in casework using the DNA SenCE post-PCR purification technique T. Gross, J. Thomson, S. Kutranov Forensic Science.

A comparison of AmpFlSTR Identifiler™ Kit versus AmpFlSTR Identifiler Plus™ Kit in challenging bone samples by using normal and increased PCR cycle number

R. Jacewicz, M. Jedrzejczyk, M. Ludwikowska, J. Berent

Population data of 8 X-STRs in South Italy (Calabria) using the Mentype® Argus X-8 PCR Amplification Kit (Biotype) A. Barbaro, P. Cormaci, S. Votano,

Distribution of Y chromosome haplogroup Q in Greenlanders

Introducing a latent variable approach for finding populations in a forensic DNA database Maarten Kruijver Forensic Science International: Genetics.

Determination of siblings: A special case report from Halle

R. Jacewicz, M. Jedrzejczyk, J. Berent

Paternity investigation experience with a 40 autosomal SNP panel

Semen detection: A retrospective overview from 2010

Application of less primer method to commercial kits

Simulated approach to estimate the number and combination of known/unknown contributors in mixed DNA samples using 15 short tandem repeat loci Sho Manabe,

Sho Manabe, Yuya Hamano, Chihiro Kawai, Chie Morimoto, Keiji Tamaki

Effect of linkage on sibship determination based on likelihood ratio

Antoinette A. Westen, Titia Sijen

mixsep: An R-package for DNA mixture separation

Interpretation of complex DNA profiles using Tippett plots

Monique Wesselink, Irene Kuiper

Effects of the most common methods for the enhancement of latent fingerprints on DNA extraction from forensic samples S. Gino, M. Omedei Forensic Science.

Dmitriy A. Khodakov, Anastasia S. Khodakova, Adrian Linacre, Amanda V

A comparative study of two extraction methods routinely used for DNA recovery from simulated post coital samples T. Mudariki, H. Pallikarana-Tirumala,

Improved performance for forensic casework: Extraction and isolation updates for the Maxwell® 16 instrument M. Lindner, P.V. Mandrekar, J. Bessetti,

Genetic data for the locus SE33 in a Southern Italy population with AmpFlSTR NGM SElect™ PCR amplification kit A. Barbaro, P. Cormaci, A. La Marca Forensic.

Development of a 24-plex Y chromosomal STR loci typing system

Statistical aspects of familial searching

L. Zha, L.B. Yun, H.B. Luo, J. Yan, Y.P. Hou

First application of the Investigator DIPplex indels typing kit for the analysis of ancient DNA samples C. Hollard, F. Mendisco, C. Keyser, E. Crubézy,

Discrepancies between forensic DNA databases

A.M. Ölçen, G. Filoğlu, H. Altunçul, S. Erdem, Ö. Bülbül

Presentation transcript:

On the exact distribution of the numbers of alleles in DNA mixtures Torben Tvedebrink Forensic Science International: Genetics Supplement Series Volume 4, Issue 1, Pages e278-e279 (January 2013) DOI: 10.1016/j.fsigss.2013.10.142 Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Recursion showing how to obtain α2 from α1. Forensic Science International: Genetics Supplement Series 2013 4, e278-e279DOI: (10.1016/j.fsigss.2013.10.142) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Probabilities of observing n alleles for L=10 and m=1, …, 8 using Danish allele frequencies for the SGM Plus loci. The dashed curves show probabilities for θ=0.03. Forensic Science International: Genetics Supplement Series 2013 4, e278-e279DOI: (10.1016/j.fsigss.2013.10.142) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Monte Carlo based estimate of P(D) plotted against θ for various numbers of observed alleles, n. Forensic Science International: Genetics Supplement Series 2013 4, e278-e279DOI: (10.1016/j.fsigss.2013.10.142) Copyright © 2013 Elsevier Ireland Ltd Terms and Conditions