Extracellular and standard University of Wisconsin solutions provide equivalent preservation of myocardial function Davis C. Drinkwater, MDa, Eli T.

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Presentation transcript:

Extracellular and standard University of Wisconsin solutions provide equivalent preservation of myocardial function Davis C. Drinkwater, MDa, Eli T. Ziv, MSa, Hillel Laks, MDa, Jeong Ryul Lee, MDa, Sunita Bhuta, MDb, Ehud Rudis, MDa, Paul Chang, BSa The Journal of Thoracic and Cardiovascular Surgery Volume 110, Issue 3, Pages 738-745 (September 1995) DOI: 10.1016/S0022-5223(95)70106-0 Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 1 Diagram of isolated perfusion circuit. Blood from support animal can be pumped to either aortic root or to adjustable-height reservoir that supplies left atrium. After load is determined by adjustable-height aortic column. Cardiac output can be measured by collecting coronary sinus effluent via pulmonary artery cannula plus overflow from aortic column. A, Femoral artery; V, femoral vein; LA, left atrium; LV, left ventricle; RA, right atrium; RV, right ventricle; PA, pulmonary artery; Ao, aorta; HR, heated reservoir containing blood cardioplegia (see text). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 738-745DOI: (10.1016/S0022-5223(95)70106-0) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 2 No significant difference in SWI was noted between extra cellular UW and intracellular UW solutions at each level of LVEDP. LA, Left atrial pressure (mm Hg). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 738-745DOI: (10.1016/S0022-5223(95)70106-0) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 3 No significant difference between extracellular UW and intracellular UW solutions was noted for high-energy phosphates ATP, ADP, AMP, and creatine phosphate (CP). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 738-745DOI: (10.1016/S0022-5223(95)70106-0) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 4 No significant difference in myocardial water content was noted between extracellular UW and intracellular UW solutions. The Journal of Thoracic and Cardiovascular Surgery 1995 110, 738-745DOI: (10.1016/S0022-5223(95)70106-0) Copyright © 1995 Mosby, Inc. Terms and Conditions