Clinical Strategies to Enhance Posttransplant Immune Reconstitution

Slides:



Advertisements
Similar presentations
A Simplified Procedure for Hematopoietic Stem Cell Amplification Using a Serum-Free, Feeder Cell-Free Culture System Ian M. Rogers, Nobuko Yamanaka, Robert.
Advertisements

Evidence of B Cell Immune Responses to Acute Lymphoblastic Leukemia in Murine Allogeneic Hematopoietic Stem Cell Transplantation Recipients Treated with.
Hematopoietic Stem Cell Transplantation in Australia and New Zealand,  
Steven Joffe, Michelle M. Mello, E. Francis Cook, Stephanie J. Lee 
Galactomannan Antigen Enzyme-Linked Immunosorbent Assay for Diagnosis of Invasive Aspergillosis after Hematopoietic Stem Cell Transplantation  Patrick.
Adverse Clinical Consequences of Hyperglycemia from Total Parenteral Nutrition Exposure during Hematopoietic Stem Cell Transplantation  Patricia M. Sheean,
Michael A. Pulsipher, Christina Peters, Ching-Hon Pui 
How to Treat MDS without Stem Cell Transplantation
Steven Joffe, Michelle M. Mello, E. Francis Cook, Stephanie J. Lee 
Vaccination of Children following Allogeneic Stem Cell Transplantation
Allogeneic Stem Cell Transplantation in Myelofibrosis
World Marrow Donor Association Crisis Response, Business Continuity, and Disaster Recovery Guidelines  Julia Pingel, Cullen Case, Beth Amer, Raymond A.
NCI, NHLBI/PBMTC First International Conference on Late Effects After Pediatric Hematopoietic Cell Transplantation: Persistent Immune Deficiency in Pediatric.
Adverse Clinical Consequences of Hyperglycemia from Total Parenteral Nutrition Exposure during Hematopoietic Stem Cell Transplantation  Patricia M. Sheean,
CMV Seropositivity and Viremia Drive T-Cell Reconstitution after CD34-Selected Allogeneic HCT  Christina Cho, Patrick Hilden, Ioannis Politikos, Taylor.
Edward Copelan, James T. Casper, Shelly L. Carter, Jo-Anne H
Transplantation of Umbilical Cord Blood–Derived Cells for Novel Indications in Regenerative Therapy or Immune Modulation: A Scoping Review of Clinical.
Sabina Kersting, Leo F. Verdonck 
Access to Hematopoietic Cell Transplantation in the United States
Caroline F. Morrison, Donna M
Immune Reconstitution after Allogeneic Hematopoietic Cell Transplantation in Children  Coco de Koning, Maud Plantinga, Paul Besseling, Jaap Jan Boelens,
Cytomegalovirus Infection after Allogeneic Transplantation: Comparison of Cord Blood with Peripheral Blood and Marrow Graft Sources  Christopher M. Walker,
New Light Chain Amyloid Response Criteria Help Risk Stratification of Patients by Day 100 after Autologous Hematopoietic Cell Transplantation  Anita D'Souza,
A Process to Facilitate Decision Making in Pediatric Stem Cell Transplantation: The Individualized Care Planning and Coordination Model  Justin N. Baker,
Controversies in Lymphoma: The Role of Hematopoietic Cell Transplantation for Mantle Cell Lymphoma and Peripheral T Cell Lymphoma  Peter Dreger, Ginna.
Paul Szabolcs, Donna Niedzwiecki 
Follicular Lymphoma: Prognostic Factors, Conventional Therapies, and Hematopoietic Cell Transplantation  Laurie H. Sehn, Timothy S. Fenske, Ginna G. Laport 
John R. Wingard, M. D. , Alan K. Leahigh, Dennis Confer, M. D
Improvement of Pulmonary Function with Imatinib Mesylate in Bronchiolitis Obliterans Following Allogeneic Hematopoietic Cell Transplantation  Navneet.
Visualizing the Immune Synapse
Enrico Velardi, Jennifer J
Cell-Based Therapy Using Umbilical Cord Blood for Novel Indications in Regenerative Therapy and Immune Modulation: An Updated Systematic Scoping Review.
B Cells and Transplantation: An Educational Resource
Sarah A. Holstein, Paul G. Richardson, Jacob P. Laubach, Philip L
Allogeneic Hematopoietic Stem Cell Transplantation in Adult Acute Lymphocytic Leukemia: Impact of Donor Source on Survival  Priya Kumar, Todd E. Defor,
Favorable Overall Survival with Fully Myeloablative Allogeneic Stem Cell Transplantation for Follicular Lymphoma  John Kuruvilla, Gregory Pond, Richard.
Eva Guinan, Leo Luzmik, Rupert Handgretinger, Ann Woolfrey 
Impact of Donor and Recipient Sex and Parity on Outcomes of HLA-Identical Sibling Allogeneic Hematopoietic Stem Cell Transplantation  Alison W. Loren,
Predonation Health-Related Quality of Life Scores Predict Time to Recovery in Hematopoietic Stem Cell Donors  Annelies Billen, J. Alejandro Madrigal,
Allogeneic Stem Cell Transplantation for Aplastic Anemia
The Hematopoietic Cell Transplant Pharmacist: Roles, Responsibilities, and Recommendations from the ASBMT Pharmacy Special Interest Group  Amber B. Clemmons,
Regression Models for Hazard Rates Versus Cumulative Incidence Probabilities in Hematopoietic Cell Transplantation Data  Brent R. Logan, Mei-Jie Zhang,
HLA-Mismatched, Noninherited Maternal Antigen–Matched Unrelated Cord Blood Transplantations Have Superior Survival: How HLA Typing the Cord Blood Donor's.
Pauline Damien, David S. Allan 
ASBMT and CBMTG Release Choosing Wisely BMT Recommendations
Comparison of T Cell Subset Recovery after Cord Blood and CD34-Selected Pbsc Transplantation  Christina Cho, Ioannis Politikos, Patrick Hilden, Taylor.
Galactomannan Antigen Enzyme-Linked Immunosorbent Assay for Diagnosis of Invasive Aspergillosis after Hematopoietic Stem Cell Transplantation  Patrick.
Gerard Socié, K. Scott Baker, Smita Bhatia 
What is quality in a transplant program?
Issues of Aging and Geriatric Medicine: Relevance to Cancer Treatment and Hematopoietic Reconstitution  William B. Ershler, Andrew S. Artz, Evan T. Keller 
Participation in Clinical Research: Perspectives of Adult Patients and Parents of Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation 
Richard Mitchell, John E. Wagner, Claudio G
Chimeric Antigen Receptor–Modified T Cells: Clinical Translation in Stem Cell Transplantation and Beyond  Stanley R. Riddell, Michael C. Jensen, Carl.
Allogeneic Hematopoietic Stem Cell Transplantation in FLT3-ITD–Positive Acute Myelogenous Leukemia: The Role for FLT3 Tyrosine Kinase Inhibitors Post-
Unrelated Donor Hematopoietic Cell Transplantation: Factors Associated with a Better HLA Match  Jason Dehn, Mukta Arora, Stephen Spellman, Michelle Setterholm,
Improving the Informed Consent Process in Hematopoietic Cell Transplantation: Patient, Caregiver, and Provider Perspectives  Minakshi Raj, Sung Won Choi,
Blood and Marrow Transplant Handbook
Young Female Donors Do Not Increase the Risk of Graft-versus-Host Disease or Impact Overall Outcomes in Pediatric HLA-Matched Sibling Hematopoietic Stem.
Bernard Maybury, Gordon Cook, Guy Pratt, Kwee Yong, Karthik Ramasamy 
Mammen Chandy  Biology of Blood and Marrow Transplantation 
Reduced Intensity Conditioning for Allogeneic Hematopoietic Cell Transplantation: Current Perspectives  Brenda M. Sandmaier, Stephen Mackinnon, Richard.
Treatment versus Transplant for Challenging Hematologic Disorders
Clinical Outcome following Autologous and Allogeneic Blood and Marrow Transplantation for Relapsed Diffuse Large-Cell Non-Hodgkin’s Lymphoma  Ivan Aksentijevich,
Hematopoietic Stem Cell Transplantation in Australia and New Zealand,  
Mary Eapen  Biology of Blood and Marrow Transplantation 
Futility of Relapsed Diffuse Large B Cell Lymphoma Transplantation?
Correlation of Infused CD3+CD8+ Cells with Single-Donor Dominance after Double-Unit Cord Blood Transplantation  Filippo Milano, Shelly Heimfeld, Ted Gooley,
In Memoriam: E. Donnall Thomas
Long-Term Results Of Autologous Hematopoietic Cell Transplantation For Peripheral T Cell Lymphoma: The Stanford Experience  Andy I. Chen, Alex McMillan,
Optimal Donor Selection: Beyond HLA
Presentation transcript:

Clinical Strategies to Enhance Posttransplant Immune Reconstitution Irwin D. Bernstein, Richard L. Boyd, Marcel R.M. van den Brink  Biology of Blood and Marrow Transplantation  Volume 14, Issue 1, Pages 94-99 (January 2008) DOI: 10.1016/j.bbmt.2007.10.003 Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 IL-7, KGF and donor T/NK precursors enhance posttransplant T cell reconstitution. Biology of Blood and Marrow Transplantation 2008 14, 94-99DOI: (10.1016/j.bbmt.2007.10.003) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Sex steroids are key to the degradation of the adult immune system and the immune system can be rejuvenated after regrowth of the thymus. Biology of Blood and Marrow Transplantation 2008 14, 94-99DOI: (10.1016/j.bbmt.2007.10.003) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions