Beata Seeber, M. D. , M. S. C. E. , Mary D. Sammel, Sc. D

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Presentation transcript:

Panel of markers can accurately predict endometriosis in a subset of patients Beata Seeber, M.D., M.S.C.E., Mary D. Sammel, Sc.D., Xuejun Fan, M.D., Ph.D., George L. Gerton, Ph.D., Alka Shaunik, M.D., Jesse Chittams, M.S., Kurt T. Barnhart, M.D., M.S.C.E. Fertility and Sterility Volume 89, Issue 5, Pages 1073-1081 (May 2008) DOI: 10.1016/j.fertnstert.2007.05.014 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Marker concentrations by study groups, showing the overlap in concentrations of the individual markers among the endometriosis (endo) and control groups. Fertility and Sterility 2008 89, 1073-1081DOI: (10.1016/j.fertnstert.2007.05.014) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Marker classification tree optimizing sensitivity. The class assignment of subjects in each node is shown under the node number. Class 0 is the control group, and class 1 is the endometriosis group. Bars give a graphical representation of the proportion of subjects from each group assigned to that child node. Splitting variables are shown in the parent node, with the cutoff for the split shown above the child node in gray. N = number of subjects. Fertility and Sterility 2008 89, 1073-1081DOI: (10.1016/j.fertnstert.2007.05.014) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Marker classification tree optimizing specificity. The class assignment of subjects in each node is shown under the node number. Class 0 is the control group, and class 1 is the endometriosis group. Bars give a graphical representation of the proportion of subjects from each group assigned to that child node. Splitting variables are shown in the parent node, with the cutoff for the split shown above the child node in gray. N = number of subjects. Fertility and Sterility 2008 89, 1073-1081DOI: (10.1016/j.fertnstert.2007.05.014) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 4 Marker classification tree with 100% sensitivity. The class assignment of subjects in each node is shown under the node number. Class 0 is the control group, and class 1 is the endometriosis group. Bars give a graphical representation of the proportion of subjects from each group assigned to that child node. Splitting variables are shown in the parent node, with the cutoff for the split shown above the child node in gray. N = number of subjects. Fertility and Sterility 2008 89, 1073-1081DOI: (10.1016/j.fertnstert.2007.05.014) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions